Alzheimer's disease (AD) is a major cause of dementia in older adults and is fast becoming
a major societal and economic burden due to an increase in life expectancy. Age seems to …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder with a long latency in
the" prodromal" stage, for which there are currently no effective treatments. It is generally …

Amyloidosis is a condition involving a disparate group of pathologies characterized by the
extracellular deposition of insoluble fibrils composed of broken-down proteins. These …

In the 1970s, calcium-activated potassium currents were recorded for the first time. In
10years, this Ca2+-activated potassium channel was identified in rat skeletal muscle …

Neural synchrony in brain circuits is the mainstay of cognition, including memory processes.
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that disrupts neural …

Potassium ions can cross both the outer and inner mitochondrial membranes by means of
multiple routes. A few potassium-permeable ion channels exist in the outer membrane, while …

Amyloid-β (1–42)[Aβ (1–42)] oligomer accumulations are associated with physiologic
alterations in the brains of individuals with Alzheimer's disease. In this study, we …

Aggregation of Aβ peptides is a key contributor to the etiology of Alzheimer's disease. Being
intrinsically disordered, monomeric Aβ is susceptible to conformational excursions …

The possibilities of using nanoparticle materials based on cerium dioxide (CNPs) are
exciting since they are low toxic and have specific redox, antiradical properties. It can be …

While recent advances in diagnostics and therapeutics offer promising new approaches for
Alzheimer's disease (AD) diagnosis and treatment, there is still an unmet need for an …