Local anesthetic systemic toxicity: current perspectives

K El-Boghdadly, A Pawa, KJ Chin - Local and regional anesthesia, 2018 - Taylor & Francis
Local anesthetic systemic toxicity (LAST) is a life-threatening adverse event that may occur
after the administration of local anesthetic drugs through a variety of routes. Increasing use …

The third American Society of Regional Anesthesia and Pain Medicine practice advisory on local anesthetic systemic toxicity: executive summary 2017

JM Neal, MJ Barrington, MR Fettiplace… - Regional Anesthesia & …, 2018 - rapm.bmj.com
Abstract The American Society of Regional Anesthesia and Pain Medicine's Third Practice
Advisory on local anesthetic systemic toxicity is an interim update from its 2010 advisory …

Updates in our understanding of local anaesthetic systemic toxicity: a narrative review

AJR Macfarlane, M Gitman, KJ Bornstein… - …, 2021 - Wiley Online Library
Despite advances in clinical practice, local anaesthetic systemic toxicity continues to occur
with the therapeutic use of local anaesthesia. Patterns of presentation have evolved over …

Local anesthetic systemic toxicity: a narrative literature review and clinical update on prevention, diagnosis, and management

M Gitman, MR Fettiplace, GL Weinberg… - Plastic and …, 2019 - journals.lww.com
Background: The objective of this narrative review of local anesthetic systemic toxicity is to
provide an update on its prevention, diagnosis, and management. Methods: The authors …

Adjunct medications for peripheral and neuraxial anesthesia

PI Emelife, MR Eng, BL Menard, AS Myers… - Best Practice & …, 2018 - Elsevier
Regional and neuraxial anesthesia can provide a safer perioperative experience, greater
satisfaction, reduced opioid consumption, and reduction of pain, while minimizing side …

Local anesthetic toxicity in the geriatric population

R Waldinger, G Weinberg, M Gitman - Drugs & aging, 2020 - Springer
This article provides a concise overview of local anesthetic systemic toxicity, its history,
mechanisms, risk factors, prevention, clinical presentation, and treatment, with a special …

Local anesthetic dosing and toxicity of adult truncal catheters: a narrative review of published practice

B Bungart, L Joudeh, M Fettiplace - Regional Anesthesia & Pain …, 2024 - rapm.bmj.com
Background/importance Anesthesiologists frequently use truncal catheters for postoperative
pain control but with limited characterization of dosing and toxicity. Objective We reviewed …

Local anesthetics and steroids: contraindications and complications-clinical update

T Šimurina, B Mraović, M Župčić, S Graf Župčić… - Acta Clinica …, 2019 - hrcak.srce.hr
Sažetak The objective of this clinical update, based on recently published literature, was to
discuss incidence and characteristics of the most relevant clinical adverse effects associated …

Regional nerve blocks—best practice strategies for reduction in complications and comprehensive review

EM Helander, AJ Kaye, MR Eng, PI Emelife… - Current pain and …, 2019 - Springer
Abstract Purpose of Review Understanding the etiologies of the complications associated
with regional anesthesia and implementing methods to reduce their occurrence provides an …

Local anesthetic dosing and toxicity of pediatric Truncal catheters: a narrative review of published practice

M Fettiplace, L Joudeh, B Bungart… - Regional Anesthesia & …, 2024 - rapm.bmj.com
Background/importance Despite over 30 years of use by pediatric anesthesiologists,
standardized dosing rates, dosing characteristics, and cases of toxicity of truncal nerve …