Physics-based computational and theoretical approaches to intrinsically disordered proteins
Highlights•Liquid-liquid phase separation underlies the formation of membraneless
organelles within cells.•Theory and molecular simulations help to relate interactions at the …
organelles within cells.•Theory and molecular simulations help to relate interactions at the …
A cold limit to adaptation in the sea
LS Peck - Trends in Ecology & Evolution, 2016 - cell.com
Temperature affects biological functions by altering reaction rates. Physiological rates
usually double to treble for every 10° C rise, and 1–4 fold encompasses normal biological …
usually double to treble for every 10° C rise, and 1–4 fold encompasses normal biological …
Heightened cold-denaturation of proteins at the ice–water interface
The process of freezing proteins is widely used in applications ranging from processing and
storage of biopharmaceuticals to cryo-EM analysis of protein complexes. The formation of an …
storage of biopharmaceuticals to cryo-EM analysis of protein complexes. The formation of an …
Molecular determinant of the effects of hydrostatic pressure on protein folding stability
CR Chen, GI Makhatadze - Nature communications, 2017 - nature.com
Hydrostatic pressure is an important environmental variable that plays an essential role in
biological adaptation for many extremophilic organisms (for example, piezophiles). Increase …
biological adaptation for many extremophilic organisms (for example, piezophiles). Increase …
Utilization of creep ringing and bioinformatic modelling in study of cold denatured pea protein emulsions
Pea protein is a popular and sustainable plant-based protein with broad applications in the
food industry. However, functionalities such as emulsification are still lacking. Protein …
food industry. However, functionalities such as emulsification are still lacking. Protein …
Physicochemical characterization of changes in pea protein as the result of cold extrusion
Pea protein is a popular plant-based protein for mimicking textures in meat and dairy
analogues which are more sustainable than their animal-based counterparts. However …
analogues which are more sustainable than their animal-based counterparts. However …
Quantitative structure-property relationships of thermoset pea protein gels with ethanol, shear, and sub-zero temperature pretreatments
Pea protein is often processed to alter the protein's native structure, enhancing desirable
textures in meat and dairy analog products. Cold denaturation is a universal phenomenon in …
textures in meat and dairy analog products. Cold denaturation is a universal phenomenon in …
[HTML][HTML] Protein unfolding mechanisms and their effects on folding experiments
LJ Lapidus - F1000Research, 2017 - ncbi.nlm.nih.gov
In this review, I discuss the various methods researchers use to unfold proteins in the lab in
order to understand protein folding both in vitro and in vivo. The four main techniques …
order to understand protein folding both in vitro and in vivo. The four main techniques …
An alternative explanation of the cononsolvency of poly (N-isopropylacrylamide) in water–methanol solutions
A Pica, G Graziano - Physical Chemistry Chemical Physics, 2016 - pubs.rsc.org
Cononsolvency refers to the experimental finding that poly (N-isopropylacrylamide),
PNIPAM, has a coil conformation in both pure water and pure methanol, at 20° C and 1 atm …
PNIPAM, has a coil conformation in both pure water and pure methanol, at 20° C and 1 atm …
Cold survival strategies for bacteria, recent advancement and potential industrial applications
AS Dhaulaniya, B Balan, M Kumar, PK Agrawal… - Archives of …, 2019 - Springer
Microorganisms have evolved themselves to thrive under various extreme environmental
conditions such as extremely high or low temperature, alkalinity, and salinity. These …
conditions such as extremely high or low temperature, alkalinity, and salinity. These …