Vitamins and type 2 diabetes mellitus

R Valdés-Ramos, GL Ana Laura… - … Metabolic & Immune …, 2015 - ingentaconnect.com
The present review evaluates the relationship between type 2 diabetes mellitus and
individual or combined vitamins. Antioxidant vitamins A, C and E are found decreased in …

Implication of hyperhomocysteinemia in blood retinal barrier (BRB) dysfunction

A Tawfik, YA Samra, NM Elsherbiny, M Al-Shabrawey - Biomolecules, 2020 - mdpi.com
Elevated plasma homocysteine (Hcy) level, known as hyperhomocysteinemia (HHcy) has
been linked to different systemic and neurological diseases, well-known as a risk factor for …

Germline genetic polymorphisms may influence chemotherapy response and disease outcome in osteosarcoma: a pilot study

RE Windsor, SJ Strauss, C Kallis, NE Wood… - Cancer, 2012 - Wiley Online Library
BACKGROUND: Osteosarcoma is the most common malignant bone tumor in children and
young people. Efficacy of multiagent MAP (methotrexate, doxorubicin [Adriamycin], cisplatin) …

Homocysteine: a potential biomarker for diabetic retinopathy

A Tawfik, R Mohamed, NM Elsherbiny… - Journal of clinical …, 2019 - mdpi.com
Diabetic retinopathy (DR) is the most common cause of blindness in people under the age of
65. Unfortunately, the current screening process for DR restricts the population that can be …

Metabolic correction in the management of diabetic peripheral neuropathy: improving clinical results beyond symptom control

JR Miranda-Massari, MJ Gonzalez… - Current clinical …, 2011 - ingentaconnect.com
Current Clinical Management Guidelines of Diabetic Peripheral Neuropathy (DPN) are
based on adequate glucose control and symptomatic pain relief. However, meticulous …

Homocysteine and age-related central nervous system diseases: role of inflammation

A Tawfik, NM Elsherbiny, Y Zaidi… - International journal of …, 2021 - mdpi.com
Hyperhomocysteinemia (HHcy) is remarkably common among the aging population. The
relation between HHcy and the development of neurodegenerative diseases, such as …

Ethnogeographic Prevalence and Implications of the 677C>T and 1298A>C MTHFR Polymorphisms in Us Primary Care Populations

JS Graydon, K Claudio, S Baker, M Kocherla… - Biomarkers in …, 2019 - Taylor & Francis
Aim: Variants of the MTHFR gene have been associated with a wide range of diseases.
Materials & methods: The present study analyzed data from clinical genotyping of MTHFR …

Effects of Common Polymorphisms in the MTHFR and ACE Genes on Diabetic Peripheral Neuropathy Progression: a Meta-Analysis

S Wu, Y Han, Q Hu, X Zhang, G Cui, Z Li… - Molecular neurobiology, 2017 - Springer
Diabetic peripheral neuropathy (DPN) is a microvascular complication of diabetes mellitus.
The aim of this meta-analysis was to evaluate the effects of methylenetetrahydrofolate …

Association of ACE and MTHFR genetic polymorphisms with type 2 diabetes mellitus: Susceptibility and complications

A Settin, R El-Baz, A Ismaeel… - Journal of the Renin …, 2015 - journals.sagepub.com
Hypothesis/introduction: Polymorphisms of angiotensin converting enzyme (ACE) and
methylene-tetrahydrofolate reductase (MTHFR) genes have been proposed to be …

An updated meta-analysis of methylenetetrahydrofolate reductase gene 677C/T polymorphism with diabetic nephropathy and diabetic retinopathy

W Niu, Y Qi - Diabetes research and clinical practice, 2012 - Elsevier
Studies investigating the association of methylenetetrahydrofolate reductase (MTHFR) gene
677C/T polymorphism with diabetic nephropathy and diabetic retinopathy have so far …