Protein cages: from fundamentals to advanced applications

TGW Edwardson, MD Levasseur, S Tetter… - Chemical …, 2022 - ACS Publications
Proteins that self-assemble into polyhedral shell-like structures are useful molecular
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …

50th Anniversary Perspective: A Perspective on Polyelectrolyte Solutions

M Muthukumar - Macromolecules, 2017 - ACS Publications
From the beginning of life with the information-containing polymers until the present era of a
plethora of water-based materials in health care industry and biotechnology, polyelectrolytes …

Mechanisms of virus assembly

JD Perlmutter, MF Hagan - Annual review of physical chemistry, 2015 - annualreviews.org
Viruses are nanoscale entities containing a nucleic acid genome encased in a protein shell
called a capsid and in some cases are surrounded by a lipid bilayer membrane. This review …

Multifunctional plant virus nanoparticles: An emerging strategy for therapy of cancer

M Azizi, M Shahgolzari, S Fathi‐Karkan… - Wiley …, 2023 - Wiley Online Library
Cancer therapy requires sophisticated treatment strategies to obtain the highest success.
Nanotechnology is enabling, revolutionizing, and multidisciplinary concepts to improve …

On virus growth and form

R Zandi, B Dragnea, A Travesset, R Podgornik - Physics Reports, 2020 - Elsevier
We review approaches aimed at deciphering the physical mechanisms responsible for viral
structure and assembly. We discuss the basic principles of condensed matter physics …

Physics of viral dynamics

RF Bruinsma, GJL Wuite, WH Roos - Nature Reviews Physics, 2021 - nature.com
Viral capsids are often regarded as inert structural units, but in actuality they display
fascinating dynamics during different stages of their life cycle. With the advent of single …

Modeling viral capsid assembly

MF Hagan - Advances in Chemical Physics: Volume 155, 2014 - Wiley Online Library
Viruses play a role in a significant portion of human diseases, as well as those of other
animals, plants, and bacteria. This chapter focuses on the use of theoretical and …

Stimulus-responsive assembly of nonviral nucleocapsids

M Hori, A Steinauer, S Tetter, J Hälg, EM Manz… - Nature …, 2024 - nature.com
Controlled assembly of a protein shell around a viral genome is a key step in the life cycle of
many viruses. Here we report a strategy for regulating the co-assembly of nonviral proteins …

Measurements of the self-assembly kinetics of individual viral capsids around their RNA genome

RF Garmann, AM Goldfain… - Proceedings of the …, 2019 - National Acad Sciences
Self-assembly is widely used by biological systems to build functional nanostructures, such
as the protein capsids of RNA viruses. But because assembly is a collective phenomenon …

Recent applications of synchrotron radiation and neutrons in the study of soft matter

T Narayanan, H Wacklin, O Konovalov… - Crystallography …, 2017 - Taylor & Francis
The broad range of applications of synchrotron and neutron scattering in the investigation of
soft condensed matter is reviewed. Appropriate combinations of these techniques allow …