Many important biological functions and processes are reflected in cell and tissue
mechanical properties such as elasticity and viscosity. However, current techniques used for …

Nuclear lamins are type V intermediate filament proteins that polymerize into complex
filamentous meshworks at the nuclear periphery and in less structured forms throughout the …

Maintaining and modulating mechanical anisotropy is essential for biological processes.
However, how this is achieved at the microscopic scale in living soft matter is not always …

During cancer metastasis, tumor cells undergo significant deformation in order to traverse
through endothelial cell junctions in the walls of blood vessels. As cells pass through narrow …

Several techniques have been developed over the past few decades to assess the
mechanical properties of biological samples, which has fueled a rapid growth in the fields of …

The cell nucleus is a compartment in which essential processes such as gene transcription
and DNA replication occur. Although the large amount of chromatin confined in the finite …

The development of biomaterials capable of regulating cellular processes and guiding cell
fate decisions has broad implications in tissue engineering, regenerative medicine, and cell …

Metastasis remains the leading cause of cancer lethality. The'seed/soil'hypothesis provides
the framework to explain this cancer phenomenon where the concept of organotropism has …

How migrating cells differentially adapt and respond to extracellular track geometries
remains unknown. Using intravital imaging, we demonstrate that invading cells exhibit …

Neural tube closure (NTC) is a complex process of embryonic development involving
molecular, cellular, and biomechanical mechanisms. While the genetic factors and …