Seizure diaries and forecasting with wearables: epilepsy monitoring outside the clinic

BH Brinkmann, PJ Karoly, ES Nurse… - Frontiers in …, 2021 - frontiersin.org
It is a major challenge in clinical epilepsy to diagnose and treat a disease characterized by
infrequent seizures based on patient or caregiver reports and limited duration clinical …

Machine learning and wearable devices of the future

S Beniczky, P Karoly, E Nurse, P Ryvlin, M Cook - Epilepsia, 2021 - Wiley Online Library
Abstract Machine learning (ML) is increasingly recognized as a useful tool in healthcare
applications, including epilepsy. One of the most important applications of ML in epilepsy is …

Long-term brain network reorganization predicts responsive neurostimulation outcomes for focal epilepsy

AN Khambhati, A Shafi, VR Rao… - Science Translational …, 2021 - science.org
Responsive neurostimulation (RNS) devices, able to detect imminent seizures and to rapidly
deliver electrical stimulation to the brain, are effective in reducing seizures in some patients …

A flexible, robust, and gel-free electroencephalogram electrode for noninvasive brain-computer interfaces

S Lin, J Liu, W Li, D Wang, Y Huang, C Jia, Z Li… - Nano …, 2019 - ACS Publications
Brain–computer interfaces (BCIs) enable direct and near-instant communication between
the brain and electronic devices. One of the biggest remaining challenges is to develop an …

Dogs as a natural animal model of epilepsy

W Löscher - Frontiers in veterinary science, 2022 - frontiersin.org
Epilepsy is a common neurological disease in both humans and domestic dogs, making
dogs an ideal translational model of epilepsy. In both species, epilepsy is a complex brain …

Crowdsourcing seizure detection: algorithm development and validation on human implanted device recordings

SN Baldassano, BH Brinkmann, H Ung, T Blevins… - Brain, 2017 - academic.oup.com
There exist significant clinical and basic research needs for accurate, automated seizure
detection algorithms. These algorithms have translational potential in responsive …

Seizure prediction using undulated global and local features

MZ Parvez, M Paul - IEEE Transactions on Biomedical …, 2016 - ieeexplore.ieee.org
In this study, a seizure prediction method is proposed based on a patient-specific approach
by extracting undulated global and local features of preictal/ictal and interictal periods of …

Consistency of long-term subdural electrocorticography in humans

ES Nurse, SE John, DR Freestone… - IEEE Transactions …, 2017 - ieeexplore.ieee.org
Objective: Subdural electrocorticography (ECoG) can provide a robust control signal for a
brain-computer interface (BCI). However, the long-term recording properties of ECoG are …

Recurring functional interactions predict network architecture of interictal and ictal states in neocortical epilepsy

AN Khambhati, DS Bassett, BS Oommen, SH Chen… - eneuro, 2017 - eneuro.org
Human epilepsy patients suffer from spontaneous seizures, which originate in brain regions
that also subserve normal function. Prior studies demonstrate focal, neocortical epilepsy is …

Stochastic gradient MCMC for state space models

C Aicher, YA Ma, NJ Foti, EB Fox - SIAM Journal on Mathematics of Data …, 2019 - SIAM
State space models (SSMs) are a flexible approach to modeling complex time series.
However, inference in SSMs is often computationally prohibitive for long time series …