Abstract 'Autophagy'refers to an evolutionarily conserved process through which cellular
contents, such as damaged organelles and protein aggregates, are delivered to lysosomes …

Macrophages play an important role in tissue homeostasis, tissue remodeling, immune
response, and progression of cancer. Consequently, macrophages exhibit significant …

Cytosolic innate immune sensors are critical for host defense and form complexes, such as
inflammasomes and PANoptosomes, that induce inflammatory cell death. The sensor …

The ideal vaccine against viruses such as influenza and SARS-CoV-2 must provide a
robust, durable and broad immune protection against multiple viral variants. However …

Chimeric antigen receptor (CAR) T cell therapy has garnered significant excitement due to
its success for hematological malignancies in clinical studies leading to the US Food and …

The gut microbiota has been linked to the development of obesity and type 2 diabetes (T2D).
The underlying mechanisms as to how intestinal microbiota may contribute to T2D are only …

Ageing of the global population has become a public health concern with an important socio-
economic dimension. Ageing is characterized by an increase in the concentration of …

In recent years, a lot of scientific interest has focused on cancer immunotherapy. Although
chronic inflammation has been described as one of the hallmarks of cancer, acute …

Anatomic pathology studies performed over 150 years ago revealed that excessive
activation of coagulation occurs in the setting of inflammation. However, it has taken over a …

Asthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly
overlap in the human interactome. The concept of “one‐airway‐one‐disease,” coined over …