Abstract P2Y receptors are G-protein-coupled receptors (GPCRs) for extracellular
nucleotides. There are eight mammalian P2Y receptor subtypes (P2Y 1, P2Y 2, P2Y 4, P2Y …

In the central nervous system, NG2‐glia represent a neural cell population that is distinct
from neurons, astrocytes, and oligodendrocytes. While in the past the main role ascribed to …

Myelin degeneration occurs in neurodegenerative diseases and aging. In these conditions,
resident oligodendrocyte progenitor cells (OPCs) differentiate into oligodendrocytes that …

Oligodendrocytes are neuroglial cells responsible, within the central nervous system, for
myelin sheath formation that provides an electric insulation of axons and accelerate the …

Myelin is the lipid-rich structure formed by oligodendrocytes (OLs) that wraps the axons in
multilayered sheaths, assuring protection, efficient saltatory signal conduction and metabolic …

In recent years, a substantial body of evidence has emerged demonstrating that purine and
pyrimidine synthesis and metabolism play major roles in controlling embryonic and fetal …

Oligodendrocytes are the myelinating cells of the central nervous system that constitute
about 5 to 10% of the total glial population. These cells are responsible for myelin sheath …

While the formation of myelin by oligodendrocytes is critical for the function of the central
nervous system, the molecular mechanism controlling oligodendrocyte differentiation …

Abstract P2Y receptors are G-protein-coupled receptors (GPCRs) for extracellular
nucleotides. There are eight mammalian P2Y receptor subtypes divided into two subgroups …

Oligodendrocytes are the myelin-forming cells of the CNS. They differentiate from
oligodendrocyte precursor cells (OPCs) that are produced from progenitors throughout life …