The concept of the neurovascular unit (NVU), formalized at the 2001 Stroke Progress
Review Group meeting of the National Institute of Neurological Disorders and Stroke …

Patients with Parkinson's disease have a number of specific visual disturbances. These
include changes in colour vision and contrast sensitivity and difficulties with complex visual …

Background Blood–brain barrier (BBB) disruption has been noted in animal models of
Parkinson's disease (PD) and forms the basis of the vascular hypothesis of …

Arterial spin labeling (ASL) is a non-invasive MRI technique to measure cerebral blood flow
(CBF). This review provides a practical guide and overview of the clinical applications of …

The differential diagnosis of parkinsonian syndromes is considered one of the most
challenging in neurology and error rates in the clinical diagnosis can be high even at …

Over the past three decades, neuroimaging studies—including structural, functional and
molecular modalities—have provided invaluable insights into the mechanisms underlying …

Although resting tremor, cogwheel rigidity, hypokinesia/bradykinesia and postural instability
usually dominate the clinical picture of sporadic Parkinson's disease (PD), both clinical and …

Structural and functional integrity of the cerebral vasculature ensures proper brain
development and function, as well as healthy aging. The inability of the brain to store energy …

Background The genesis of severe fatigue and disability in people following acute pathogen
invasion involves the activation of Toll-like receptors followed by the upregulation of …

There is increasing evidence for blood–brain barrier (BBB) alterations in Parkinson's
disease (PD), the second most common neurodegenerative disorder with rapidly rising …