Background Osteogenesis imperfecta (OI) is a rare heritable connective tissue disorder
primarily characterised by skeletal deformity and fragility, and an array of secondary …

Objectives The objective of this literature review was to evaluate multimodal therapies and
interventions that help prevent progression and manage pain in children with OI. Design A …

Background Osteogenesis imperfecta (OI) is a rare genetic disease characterized by bone
fragility, with a wide range in the severity of clinical manifestations. The majority of cases are …

Background Osteogenesis imperfecta (OI) is a rare, heritable connective tissue disorder
associated with a variety of symptoms, that affect individuals' quality of life (QoL) and can be …

In this large-sample study, we demonstrated that osteogenesis imperfecta (OI) significantly
impaired the quality of life (QoL) in children. Moderate/severe OI patients had worse QoL …

Abstract Background Rare bone diseases (RBDs) are a set of inherited rare diseases that
can cause disability and have a devastating impact on families affected, which may lead to a …

Purpose Measuring health-related quality of life (HRQoL) of children with suspected genetic
conditions is important for understanding the effect of interventions such as genomic …

Hospital use by patients with osteogenesis imperfecta was largely unknown. This study
found that the English NHS provides a significant number of hospital admissions to these …

Chronic pain is a common experience in osteogenesis imperfecta (OI). However, there are
few studies on this topic, and none of them emerge from psychology as a discipline. The …

Purpose Patient-reported outcome measures (PROMs) are increasingly recognized as
valuable endpoints in clinical trials. The Pediatric Outcomes Data Collection Instrument …