Thermoresponsive polymers hold great potential in the biomedical field, since they enable
the fabrication of cell sheets, in situ drug delivery and 3D-printing under physiological …

Mesenchymal stromal cells (MSCs) have been widely investigated for their therapeutic
potential in regenerative medicine, owing to their ability to home damaged tissue and serve …

Thermoresponsive surfaces, prepared by grafting of poly (N-isopropylacrylamide)(PIPAAm)
or its copolymers, have been investigated for biomedical applications. Thermoresponsive …

Medication-related osteonecrosis of the jaw (MRONJ) is a potentially severe adverse event
affecting patients with cancer and patients with osteoporosis who have been treated with …

Hepatic tissue engineering has been applied for the treatment of intractable liver diseases,
and hepatocyte sheets are promising for this purpose. However, hepatocyte sheets have …

Background Human umbilical cord-derived mesenchymal stem cell (hUC-MSC) sheets have
recently attracted attention as an alternative approach to injected cell suspensions for stem …

The mechanism and effective treatment of bisphosphonate-related osteonecrosis of the jaw
(BRONJ) are still uncertain. Our previous study revealed that zoledronate (ZOL) …

Since the initial description of medication‐related osteonecrosis of the jaw (MRONJ) almost
two decades ago, the potential pathophysiology and risk factors have been elaborated on in …

OBJECTIVE Stem cell therapy is a promising strategy for the treatment of severe cerebral
ischemia. However, targeting sufficient grafted cells to the affected area remains …

Periosteum, a highly vascularized bilayer connective tissue membrane plays an
indispensable role in the repair and regeneration of bone defects. It is involved in blood …