The physiological functions of human peroxisomes

RJA Wanders, M Baes, D Ribeiro… - Physiological …, 2023 - journals.physiology.org
Peroxisomes are subcellular organelles that play a central role in human physiology by
catalyzing a range of unique metabolic functions. The importance of peroxisomes for human …

Exosomal lipid composition and the role of ether lipids and phosphoinositides in exosome biology

T Skotland, NP Hessvik, K Sandvig, A Llorente - Journal of lipid research, 2019 - ASBMB
Exosomes are a type of extracellular vesicle released from cells after fusion of multivesicular
bodies with the plasma membrane. These vesicles are often enriched in cholesterol, SM …

Plasmalogens and chronic inflammatory diseases

JC Bozelli Jr, S Azher, RM Epand - Frontiers in physiology, 2021 - frontiersin.org
It is becoming widely acknowledged that lipids play key roles in cellular function, regulating
a variety of biological processes. Lately, a subclass of glycerophospholipids, namely …

[HTML][HTML] Plasmalogens, platelet-activating factor and beyond–Ether lipids in signaling and neurodegeneration

F Dorninger, S Forss-Petter, I Wimmer, J Berger - Neurobiology of disease, 2020 - Elsevier
Glycerol-based ether lipids including ether phospholipids form a specialized branch of lipids
that in mammals require peroxisomes for their biosynthesis. They are major components of …

Peroxisome-derived lipids regulate adipose thermogenesis by mediating cold-induced mitochondrial fission

H Park, A He, M Tan, JM Johnson… - The Journal of …, 2019 - Am Soc Clin Investig
Peroxisomes perform essential functions in lipid metabolism, including fatty acid oxidation
and plasmalogen synthesis. Here, we describe a role for peroxisomal lipid metabolism in …

Molecular insights into peroxisome homeostasis and peroxisome biogenesis disorders

Y Fujiki, K Okumoto, M Honsho, Y Abe - Biochimica et Biophysica Acta …, 2022 - Elsevier
Peroxisomes are single-membrane organelles essential for cell metabolism including the β-
oxidation of fatty acids, synthesis of etherlipid plasmalogens, and redox homeostasis …

Regulation of phagocytosis in macrophages by membrane ethanolamine plasmalogens

JM Rubio, AM Astudillo, J Casas, MA Balboa… - Frontiers in …, 2018 - frontiersin.org
Macrophages, as professional phagocytes of the immune system, possess the ability to
detect and clear invading pathogens and apoptotic cells through phagocytosis …

Review of eukaryote cellular membrane lipid Composition, with special attention to the fatty acids

O Ali, A Szabó - International Journal of Molecular Sciences, 2023 - mdpi.com
Biological membranes, primarily composed of lipids, envelop each living cell. The intricate
composition and organization of membrane lipids, including the variety of fatty acids they …

Cellular Plasmalogen Content Does Not Influence Arachidonic Acid Levels or Distribution in Macrophages: A Role for Cytosolic Phospholipase A2γ in Phospholipid …

P Lebrero, AM Astudillo, JM Rubio… - Cells, 2019 - mdpi.com
Availability of free arachidonic acid (AA) constitutes a rate limiting factor for cellular
eicosanoid synthesis. AA distributes differentially across membrane phospholipids, which is …

On the road to unraveling the molecular functions of ether lipids

N Jiménez‐Rojo, H Riezman - FEBS letters, 2019 - Wiley Online Library
Ether lipids are glycerolipids further classified into alkyl‐ether and alkenyl‐ether (also
termed plasmalogens) lipids. The two ether lipid subclasses share the first steps of their …