[HTML][HTML] Erythrocytes as carriers: From drug delivery to biosensors

L Koleva, E Bovt, F Ataullakhanov, E Sinauridze - Pharmaceutics, 2020 - mdpi.com
Drug delivery using natural biological carriers, especially erythrocytes, is a rapidly
developing field. Such erythrocytes can act as carriers that prolong the drug's action due to …

Iron oxide as an MRI contrast agent for cell tracking: supplementary issue

DJ Korchinski, M Taha, R Yang… - Magnetic resonance …, 2015 - journals.sagepub.com
Iron oxide contrast agents have been combined with magnetic resonance imaging for cell
tracking. In this review, we discuss coating properties and provide an overview of ex vivo …

Functionalization of novel theranostic hydrogels with kartogenin-grafted USPIO nanoparticles to enhance cartilage regeneration

W Yang, P Zhu, H Huang, Y Zheng, J Liu… - … applied materials & …, 2019 - ACS Publications
Here, kartogenin (KGN), an emerging stable nonprotein compound with the ability to
promote differentiation of bone marrow-derived mesenchymal stem cells (BMSCs) into …

SPIO nanoparticles and magnetic erythrocytes as contrast agents for biomedical and diagnostic applications

A Antonelli, M Magnani - Journal of magnetism and magnetic materials, 2022 - Elsevier
Superparamagnetic iron oxide nanoparticles (SPION) are available since many years and
some of them are already approved for human use. New applications are currently emerging …

Preparation and characterization of the collagen/cellulose nanocrystals/USPIO scaffolds loaded kartogenin for cartilage regeneration

W Yang, Y Zheng, J Chen, Q Zhu, L Feng, Y Lan… - Materials Science and …, 2019 - Elsevier
The regeneration of cartilage is a challenging problem for lack of innate abilities to mount a
sufficient healing response. Kartogenin (KGN), an emerging chondroinductive non-protein …

Reengineering red blood cells for cellular therapeutics and diagnostics

F Pierigè, N Bigini, L Rossi… - Wiley Interdisciplinary …, 2017 - Wiley Online Library
Recently optimized technologies that permit the reversible opening of nanopores across the
red blood cell membrane, give the extraordinary opportunity for reengineering human …

Engineering erythrocytes for the modulation of drugs' and contrasting agents' pharmacokinetics and biodistribution

L Rossi, F Pierigè, A Antonelli, N Bigini… - Advanced Drug Delivery …, 2016 - Elsevier
Pharmacokinetics, biodistribution, and biological activity are key parameters that determine
the success or failure of therapeutics. Many developments intended to improve their in vivo …

Development of long circulating magnetic particle imaging tracers: use of novel magnetic nanoparticles and entrapment into human erythrocytes

A Antonelli, P Szwargulski, ES Scarpa, F Thieben… - …, 2020 - Taylor & Francis
Aim: Magnetic particle imaging (MPI) is highly promising for biomedical applications, but
optimal tracers for MPI, namely superparamagnetic iron oxide-based contrast agents, are …

Red blood cells as carriers of iron oxide-based contrast agents for diagnostic applications

A Antonelli, M Magnani - Journal of biomedical nanotechnology, 2014 - ingentaconnect.com
New biomedical strategies are being developed to improve disease detection, therapeutic
monitoring, and treatment efficacy in several contexts for example in anti-angiogenic …

New strategies to prolong the in vivo life span of iron-based contrast agents for MRI

A Antonelli, C Sfara, S Battistelli, B Canonico… - PLoS …, 2013 - journals.plos.org
Superparamagnetic iron oxide (SPIO) and ultra small superparamagnetic iron oxide
(USPIO) nanoparticles have been developed as magnetic resonance imaging (MRI) contrast …