Inflammasomes are large intracellular multi-protein signalling complexes that are formed in
the cytosolic compartment as an inflammatory immune response to endogenous danger …

Cervical cancer disproportionately affects women of reproductive age, with 80% of cases
occurring in low-and middle-income countries. Persistent infection with high-risk human …

While high-risk human papillomavirus (HPV) infection is a well-established risk factor for
cervical cancer, there are likely other factors within the local microenvironment that …

Cervical human papillomavirus (HPV) infection may increase HIV risk. Since other genital
infections enhance HIV susceptibility by inducing inflammation, we assessed the impact of …

Simple Summary NLRP3 inflammasome is a cytoplasmic multiprotein complex that
assembles in response to cellular distress and promotes maturation and release of the …

Abstract Interferon-γ (IFN-γ)-induced protein 10 (IP-10 or CXCL-10) is a chemokine involved
in trafficking immune cells to inflammatory sites. Numerous studies have reported …

Persistent human papillomavirus (HPV) infection is the vital factor driving cervical
carcinogenesis; however, other features of the local cervicovaginal microenvironment (CVM) …

Inflammation has a crucial role in protection against various pathogens. The inflammasome
is an intracellular multiprotein signaling complex that is linked to pathogen sensing and …

Background This study aims to investigate the difference in vaginal microecology, local
immunity and HPV infection among childbearing-age women with different degrees of …

Inflammasomes, intracellular, multimeric protein complexes, are assembled when damage
signals stimulate nucleotide-binding oligomerization domain receptors (NLRs). Several …