Noninvasive prenatal genetic testing (NIPT) is an advance in the detection of fetal
chromosomal aneuploidies that analyzes cell-free fetal DNA in the blood of a pregnant …

Epigenetic mechanisms play instrumental roles in gene regulation during embryonic
development and disease progression. However, it is challenging to non-invasively monitor …

Cell-free DNA (cfDNA) has become a comprehensive biomarker in the fields of non-invasive
cancer detection and monitoring, organ transplantation, prenatal genetic testing and …

Background Advances have been made in the management of pregnancies in women
receiving dialysis; however, single-centre studies and small numbers of cases have so far …

The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

Down syndrome (DS) originates, in most of the cases (95%), from a full trisomy of
chromosome 21. The remaining cases are due to either mosaicism for chromosome 21 or …

Osteogenesis imperfecta (OI), or brittle bone disease, is a heterogeneous disorder
characterised by bone fragility, multiple fractures, bone deformity, and short stature. OI is a …

Cancer is a major cause of death worldwide, and an early diagnosis is required for a
favorable prognosis. Histological examination is the gold standard for cancer identification; …

Objective As the first laboratory to offer massively parallel sequencing-based noninvasive
prenatal testing (NIPT) for fetal aneuploidies, Sequenom Laboratories has been able to …

Prenatal testing in recent years has been moving toward non-invasive methods to determine
the fetal risk for genetic disorders without incurring the risk of miscarriage. Rapid progress of …