Molecular Insight into Prostate Cancer: Preventive Role of Selective Bioactive Molecules

M Jameel, H Fatma, LA Nadtochii, HR Siddique - Life, 2023 - mdpi.com
Prostate cancer (CaP) is one of the most prevalent male malignancies, accounting for a
considerable number of annual mortalities. However, the prompt identification of early-stage …

TP53 loss‐of‐function causes vulnerability to autophagy inhibition in aggressive prostate cancer

Y Zhang, XL Song, B Yu, LC Foong… - … Journal of Urology, 2022 - Wiley Online Library
Objectives TP53 loss‐of‐function is commonly found in aggressive prostate cancer.
However, a highly‐efficient therapy for this tumor subtype is still lacking. In this study, we …

Targeting DNA Repair in Prostate Cancer: Therapeutic Combinations & Disease Models

R Hanson - 2023 - repository.cam.ac.uk
Targeting prostate cancer cells with DNA repair inhibitors presents an opportunity to improve
outcomes in patients with poor prognosis cancers. There are multiple reasons which …