Abstract N6-methyladenosine (m6A) methylation is the most universal internal modification
in eukaryotic mRNA. With elaborate functions executed by m6A writers, erasers, and …

Abstract N6-methyladenosine (m6A), is the most prevalent and reversible post-
transcriptional epigenetic modification of RNA in mammals. Dysregulation of m6A …

Summary N 6-methyladenosine (m 6 A) methyltransferase Mettl3 is involved in conventional
T cell immunity; however, its role in innate immune cells remains largely unknown. Here, we …

Given its central role in immune aging, it is important to identify the regulators of thymic
involution. While conventional programmed cell death has a fundamental role in thymocyte …

Inflammation orchestrates a finely balanced process crucial for microorganism elimination
and tissue injury protection. A multitude of immune and non-immune cells, alongside various …

Age-related thymic involution compromises immune function, which leaves older adults
more vulnerable to infections and to a potentially increased risk of cancer and autoimmune …

RNA modifications are epigenetic changes that alter the structure and function of RNA
molecules, playing a crucial role in the onset, progression, and treatment of cancer. Immune …

The tumor microenvironment (TME) is a heterogeneous ecosystem comprising cancer cells,
immune cells, stromal cells, and various non-cellular components, all of which play critical …

Background RNA N6-methyladenosine (m6A) regulators are considered post-transcriptional
regulators that affect several biological functions, and their role in immunity, in particular, is …

Colorectal cancer (CRC) ranks as the third most prevalent malignancy worldwide. Despite
the gradual expansion of therapeutic options for CRC, its clinical management remains a …