Abstract Organs-on-chips (OoCs), also known as microphysiological systems or 'tissue
chips'(the terms are synonymous), have attracted substantial interest in recent years owing …

Microfluidics provides a great opportunity to create devices capable of outperforming
classical techniques in biomedical and chemical research. In this review, the origins of this …

Organ chips can recapitulate organ-level (patho) physiology, yet pharmacokinetic and
pharmacodynamic analyses require multi-organ systems linked by vascular perfusion. Here …

Abstract Coronavirus disease 2019 (COVID‐19) is a global pandemic caused by severe
acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). The models that can accurately …

Organs-on-a-chip (OOCs) are miniature tissues and organs grown in vitro that enable
modeling of human physiology and disease. The technology has emerged from converging …

Engineering cardiac tissues and organ models remains a great challenge due to the
hierarchical structure of the native myocardium. The need of integrating blood vessels brings …

Inspired by the relatively simple morphological blueprint provided by batoid fish such as
stingrays and skates, we created a biohybrid system that enables an artificial animal—a …

The devastating effects and incurable nature of hereditary and sporadic retinal diseases
such as Stargardt disease, age-related macular degeneration or retinitis pigmentosa …

An organ-on-a-chip is a microfluidic cell culture device created with microchip manufacturing
methods that contains continuously perfused chambers inhabited by living cells arranged to …

Improving the effectiveness of preclinical predictions of human drug responses is critical to
reducing costly failures in clinical trials. Recent advances in cell biology, microfabrication …