Immune checkpoint molecules function to inhibit and regulate immune response pathways
to prevent hyperactive immune activity from damaging healthy tissues. In cancer patients …

Cardiac electrophysiology is a complex system established by a plethora of inward and
outward ion currents in cardiomyocytes generating and conducting electrical signals in the …

Key events in T cell–dependent antibody responses, including affinity maturation, are
dependent on the B cell's presentation of antigen to helper T cells at critical checkpoints in …

Psoriasis is a common chronic inflammatory skin disease with no cure. It is driven by the
interleukin (IL)-23/IL-17A axis and type 17 T helper cells; however, recently, group 3 innate …

Pathogens have developed a plethora of strategies to undermine host immune defenses in
order to guarantee their survival. For large DNA viruses, these immune evasion mechanisms …

Background: Acute myeloid leukemia (AML) escape from immunosurveillance by
immunosuppression. CD200 and CD56 expression represented an independent prognostic …

Due to their need for living cells, viruses have developed adaptive evolutionary strategies to
survive and perpetuate in reservoir hosts that play a crucial role in the ecology of emerging …

Poxviruses have previously been detected in macropods with cutaneous papillomatous
lesions, however to date, no comprehensive analysis of a poxvirus from kangaroos has …

Psoriasis is a common chronic inflammatory skin disease with no cure. It is driven by the IL-
23/IL-17A axis and TH17 cells but, recently group 3 innate lymphoid cells (ILC3s) have also …

ABSTRACT The CD200-CD200 receptor (CD200R) pathway is involved in inhibition of
immune responses, and the importance of this pathway to infectious disease is highlighted …