New strategies for the transition-metal catalyzed synthesis of aliphatic amines

A Trowbridge, SM Walton, MJ Gaunt - Chemical reviews, 2020 - ACS Publications
Transition-metal catalyzed reactions that are able to construct complex aliphatic amines from
simple, readily available feedstocks have become a cornerstone of modern synthetic …

Synthesis of heterocycles via palladium-catalyzed carbonylations

XF Wu, H Neumann, M Beller - Chemical Reviews, 2013 - ACS Publications
Palladium-catalyzed coupling reactions have become a powerful tool in organic synthesis. 1
Today, there are numerous applications of palladium catalysts in the preparation of …

Palladium (II)-catalyzed alkene functionalization via nucleopalladation: stereochemical pathways and enantioselective catalytic applications

RI McDonald, G Liu, SS Stahl - Chemical reviews, 2011 - ACS Publications
The development of catalytic reactions of alkenes transformed the chemical industry in the
mid-20th century. Representative reactions included hydrogenation, oxidation …

Palladium‐catalyzed oxidative carbonylation reactions

XF Wu, H Neumann, M Beller - ChemSusChem, 2013 - Wiley Online Library
Palladium‐catalyzed coupling reactions have become a powerful tool for advanced organic
synthesis. This type of reaction is of significant value for the preparation of pharmaceuticals …

Palladium‐Catalyzed Enantioselective Heck Carbonylation with a Monodentate Phosphoramidite Ligand: Asymmetric Synthesis of (+)‐Physostigmine,(+) …

M Chen, X Wang, P Yang, X Kou… - Angewandte Chemie …, 2020 - Wiley Online Library
Reported herein is the development of the first enantioselective monodentate ligand
assisted Pd‐catalyzed domino Heck carbonylation reaction with CO. The highly …

Enantioselective Synthesis of 2‐Oxindole Spirofused Lactones and Lactams by Heck/Carbonylative Cylization Sequences: Method Development and Applications

H Hu, F Teng, J Liu, W Hu, S Luo… - Angewandte Chemie …, 2019 - Wiley Online Library
An efficient one‐pot assembly of all‐carbon spiro‐oxindole compounds from non‐oxindole‐
based materials has been developed through a palladium‐catalyzed asymmetric …

Asymmetric palladium-catalyzed carboamination reactions for the synthesis of enantiomerically enriched 2-(arylmethyl)-and 2-(alkenylmethyl) pyrrolidines

DN Mai, JP Wolfe - Journal of the American Chemical Society, 2010 - ACS Publications
The enantioselective synthesis of 2-(arylmethyl)-and 2-(alkenylmethyl) pyrrolidine
derivatives via Pd-catalyzed alkene carboamination reactions is described. These …

An asymmetric aerobic aza-Wacker-type cyclization: synthesis of isoindolinones bearing tetrasubstituted carbon stereocenters.

G Yang, C Shen, W Zhang - Angewandte Chemie (International ed …, 2012 - europepmc.org
It's all in the solvent: An enantioselective variant of an aza-Wacker-type cyclization that gives
isoindolinones containing tetrasubstituted carbon centers α to the nitrogen atom has been …

Recent advances in carbonylative difunctionalization of Alkenes

JB Peng - Advanced Synthesis & Catalysis, 2020 - Wiley Online Library
The carbonylation reaction represents one of the most powerful methods for the rapid build‐
up of carbonyl structures and has widely applied in both academic and industry fields …

Asymmetric Aza-Wacker-Type Cyclization of N-Ts Hydrazine-Tethered Tetrasubstituted Olefins: Synthesis of Pyrazolines Bearing One Quaternary or Two Vicinal …

X Kou, Q Shao, C Ye, G Yang… - Journal of the American …, 2018 - ACS Publications
We have developed an asymmetric aza-Wacker-type cyclization of N-Ts hydrazine-tethered
tetrasubstituted olefins, affording optically active pyrazolines bearing chiral tetrasubstituted …