Aging and Alzheimer's disease: comparison and associations from molecular to system level
Alzheimer's disease is the most prevalent cause of dementia, which is defined by the
combined presence of amyloid and tau, but researchers are gradually moving away from the …
combined presence of amyloid and tau, but researchers are gradually moving away from the …
Extensive recoding of the neural proteome in cephalopods by RNA editing
JJC Rosenthal, E Eisenberg - Annual Review of Animal …, 2023 - annualreviews.org
The coleoid cephalopods have the largest brains, and display the most complex behaviors,
of all invertebrates. The molecular and cellular mechanisms that underlie these remarkable …
of all invertebrates. The molecular and cellular mechanisms that underlie these remarkable …
[HTML][HTML] Trade-off between transcriptome plasticity and genome evolution in cephalopods
N Liscovitch-Brauer, S Alon, HT Porath, B Elstein… - Cell, 2017 - cell.com
RNA editing, a post-transcriptional process, allows the diversification of proteomes beyond
the genomic blueprint; however it is infrequently used among animals for this purpose …
the genomic blueprint; however it is infrequently used among animals for this purpose …
Introducing BASE: the Biomes of Australian Soil Environments soil microbial diversity database
Background Microbial inhabitants of soils are important to ecosystem and planetary
functions, yet there are large gaps in our knowledge of their diversity and ecology. The …
functions, yet there are large gaps in our knowledge of their diversity and ecology. The …
Profiling RNA editing in human tissues: towards the inosinome Atlas
Adenine to Inosine RNA editing is a widespread co-and post-transcriptional mechanism
mediated by ADAR enzymes acting on double stranded RNA. It has a plethora of biological …
mediated by ADAR enzymes acting on double stranded RNA. It has a plethora of biological …
POSTAR2: deciphering the post-transcriptional regulatory logics
Post-transcriptional regulation of RNAs is critical to the diverse range of cellular processes.
The volume of functional genomic data focusing on post-transcriptional regulation logics …
The volume of functional genomic data focusing on post-transcriptional regulation logics …
Massive A-to-I RNA editing is common across the Metazoa and correlates with dsRNA abundance
Background Adenosine to inosine (A-to-I) RNA editing is a post-transcriptional modification
catalyzed by the ADAR (adenosine deaminase that acts on RNA) enzymes, which are …
catalyzed by the ADAR (adenosine deaminase that acts on RNA) enzymes, which are …
The full-length transcriptome of C. elegans using direct RNA sequencing
NP Roach, N Sadowski, AF Alessi, W Timp… - Genome …, 2020 - genome.cshlp.org
Current transcriptome annotations have largely relied on short read lengths intrinsic to the
most widely used high-throughput cDNA sequencing technologies. For example, in the …
most widely used high-throughput cDNA sequencing technologies. For example, in the …
Rampant C-to-U deamination accounts for the intrinsically high mutation rate in SARS-CoV-2 spike gene
X Liu, X Liu, J Zhou, Y Dong, W Jiang, W Jiang - Rna, 2022 - rnajournal.cshlp.org
The high mutation rate of SARS-CoV-2 largely complicates our control of the pandemic. In
particular, it is currently unclear why the spike (S) gene has an extraordinarily high mutation …
particular, it is currently unclear why the spike (S) gene has an extraordinarily high mutation …
Genome-wide A-to-I RNA editing in fungi independent of ADAR enzymes
Yeasts and filamentous fungi do not have adenosine deaminase acting on RNA (ADAR)
orthologs and are believed to lack A-to-I RNA editing, which is the most prevalent editing of …
orthologs and are believed to lack A-to-I RNA editing, which is the most prevalent editing of …