The usage of 3D-printing for drug-eluting implants combines the advantages of a targeted
local drug therapy over longer periods of time at the precise location of the disease with a …

Bacterial infection is one of the most common complications following the implantation of
biomaterials and can lead to aseptic loosening, prosthesis failure, and even morbidity or …

A surgically implantable device is an inevitable treatment option for millions of people
worldwide suffering from diseases arising from orthopedic injuries. A global paradigm shift is …

Biopolymer-based injectable hydrogels provide great potential as bone tissue engineering
(BTE) scaffolds on account of biocompatibility, and pore interconnectivity that enables …

Introduction Combination therapies continue to improve therapeutic outcomes as currently
achieved by polypharmacy. Since the introduction of the polypill, there has been a …

Background Dexamethasone (DEX) is a well-known anti-inflammatory and
immunosuppressive drug applied broadly as an osteoinductive agent in bone remodeling …

Synthesis of a supramolecular composite hydrogel, a novel class of physical and dynamic
hydrogels, is reported. The hydrogel comprised gelatin (Gel), Zn-doped nano-hydroxyapatite …

Objective Additive manufacturing (AM), commonly known as 3D printing (3DP), has opened
new frontiers in pharmaceutical applications. This review is aimed to summarise the recent …

Productive engagement of the immune system is a persistent challenge for biomaterials
scientists. Immune engineering offers a new perspective on biomaterial design, with immune …

This article provides an overview of currently available metal AM processes for the medical
industry; outlines a step-by-step review of the typical workflow for design, manufacturing …