The JAK/STAT3 signaling pathway plays an essential role in various types of cancers.
Activation of this pathway leads to increased tumorigenic and metastatic ability, the transition …

Gastrointestinal (GI) tumors (cancers of the esophagus, gastric, liver, pancreas, colon, and
rectum) contribute to a large number of deaths worldwide. STAT3 is an oncogenic …

Colorectal cancer (CRC) is known as the third common cancer worldwide and an important
public health problem in different populations. Several genetics and environmental risk …

Background Little has been known about the role of non-coding RNA regulatory network in
the patterns of growth and invasiveness of gastric cancer (GC) development. Methods …

Colorectal cancer (CRC) is among the most frequently occurring cancers worldwide.
Baicalin is isolated from the roots of Scutellaria baicalensis and is its dominant flavonoid …

The tumor microenvironment (TME) comprises a variety of immune cells, among which T
cells exert a prominent axial role in tumor development or anti-tumor responses in patients …

Innate and acquired chemoresistance exhibited by most tumours exposed to conventional
chemotherapeutic agents account for the majority of relapse cases in cancer patients. Such …

EMT represents the dominant program within advanced stages of colon cancer, where cells
acquire migratory characteristics in order to invade secondary tissues and form metastasis …

miR‐372/373, a cluster of stem cell‐specific micro RNA s transactivated by the Wnt pathway,
has been reported to be dysregulated in various cancers, particularly colorectal cancer …

Purpose Lung cancer, the leading cause of cancer-related death worldwide, shows a poor 5-
year overall survival rate. In our previous study, we demonstrated that miR-486-5p can be a …