Is working memory domain-general or domain-specific?

N Nozari, RC Martin - Trends in cognitive sciences, 2024 - cell.com
Given the fundamental role of working memory (WM) in all domains of cognition, a central
question has been whether WM is domain-general. However, the term 'domain-general'has …

Neural algorithms and circuits for motor planning

HK Inagaki, S Chen, K Daie… - Annual review of …, 2022 - annualreviews.org
The brain plans and executes volitional movements. The underlying patterns of neural
population activity have been explored in the context of movements of the eyes, limbs …

[HTML][HTML] Thalamus-driven functional populations in frontal cortex support decision-making

W Yang, SL Tipparaju, G Chen, N Li - Nature neuroscience, 2022 - nature.com
Neurons in frontal cortex exhibit diverse selectivity representing sensory, motor and
cognitive variables during decision-making. The neural circuit basis for this complex …

[HTML][HTML] Brain-wide neural activity underlying memory-guided movement

S Chen, Y Liu, ZA Wang, J Colonell, LD Liu, H Hou… - Cell, 2024 - cell.com
Behavior relies on activity in structured neural circuits that are distributed across the brain,
but most experiments probe neurons in a single area at a time. Using multiple Neuropixels …

[HTML][HTML] Brain-wide dynamics linking sensation to action during decision-making

A Khilkevich, M Lohse, R Low, I Orsolic, T Bozic… - Nature, 2024 - nature.com
Perceptual decisions rely on learned associations between sensory evidence and
appropriate actions, involving the filtering and integration of relevant inputs to prepare and …

Superior colliculus bidirectionally modulates choice activity in frontal cortex

A Thomas, W Yang, C Wang, SL Tipparaju… - Nature …, 2023 - nature.com
Action selection occurs through competition between potential choice options. Neural
correlates of choice competition are observed across frontal cortex and downstream …

Emergence of cortical network motifs for short-term memory during learning

XW Chia, JK Tan, LF Ang, T Kamigaki… - Nature …, 2023 - nature.com
Learning of adaptive behaviors requires the refinement of coordinated activity across
multiple brain regions. However, how neural communications develop during learning …

Cross-hemispheric communication: Insights on lateralized brain functions

S Ocklenburg, ZV Guo - Neuron, 2024 - cell.com
On the surface, the two hemispheres of vertebrate brains look almost perfectly symmetrical,
but several motor, sensory, and cognitive systems show a deeply lateralized organization …

Cell type-specific connectome predicts distributed working memory activity in the mouse brain

X Ding, S Froudist-Walsh, J Jaramillo, J Jiang… - elife, 2024 - elifesciences.org
Recent advances in connectomics and neurophysiology make it possible to probe whole-
brain mechanisms of cognition and behavior. We developed a large-scale model of the …

Neuromodulation and neurophysiology on the timescale of learning and decision-making

CD Grossman, JY Cohen - Annual review of neuroscience, 2022 - annualreviews.org
Nervous systems evolved to effectively navigate the dynamics of the environment to achieve
their goals. One framework used to study this fundamental problem arose in the study of …