Using telomeric chromosomal aberrations to evaluate clastogen-induced genomic instability in mammalian cells

AD Bolzán - Chromosome Research, 2020 - Springer
Telomeres, the specialized nucleoproteic complexes localized at the physical ends of linear
eukaryotic chromosomes, play a fundamental role in maintaining chromosomal stability and …

Elevated retrotransposon activity and genomic instability in primed pluripotent stem cells

H Fu, W Zhang, N Li, J Yang, X Ye, C Tian, X Lu, L Liu - Genome Biology, 2021 - Springer
Background Naïve and primed pluripotent stem cells (PSCs) represent two different
pluripotent states. Primed PSCs following in vitro culture exhibit lower developmental …

Endogenous feline leukemia virus long terminal repeat integration site diversity is highly variable in related and unrelated domestic cats

ES Chiu, CA McDonald, RB Gagne, H Dunkleberger… - Retrovirology, 2024 - Springer
Endogenous retroviruses (ERV) are indicators of vertebrate evolutionary history and play
important roles as homeostatic regulators. ERV long terminal repeat (LTR) elements may act …

Monitoring Genomic Structural Rearrangements Resulting from Gene Editing

SM Bailey, EM Cross, L Kinner-Bibeau… - Journal of Personalized …, 2024 - mdpi.com
The cytogenomics-based methodology of directional genomic hybridization (dGH) enables
the detection and quantification of a more comprehensive spectrum of genomic structural …

Telomeres and telomerase activity in the human placenta

M Jirkovská, M Korabecná… - Telomerase and non …, 2019 - books.google.com
Placenta is a transient organ ensuring the intrauterine development of the individual. To
meet fetal requirements, rapid and continuous cell proliferation enlarges the areas of tissues …

[HTML][HTML] Chromosomal and telomeric biomarkers of normal tissue injury to evaluate risk of degenerative health effects (secondary malignancy, cardiovascular disease) …

MJ McKenna, SM Bailey - Translational Cancer Research, 2017 - tcr.amegroups.org
An overall intent of radiotherapy is to precisely target tumor cells, while minimizing
exposures to surrounding normal tissue. Despite successes in this area, there is growing …

[图书][B] Role of endogenous retrovirus in control of feline leukemia virus infection and implications for cross species transmission

ES Chiu - 2019 - search.proquest.com
Endogenous retroviruses (ERV) are markers of ancient retroviral infections, though
evolutionary forces have limited the capacity for ERV replication and virulence. While they …