The global shortage of corneal transplants has spurred an urgency in the quest for efficient
treatments. This systematic review not only provides a concise overview of the current …

Corneal failure is a highly prevalent cause of blindness. One special cause of corneal failure
occurs due to malfunction or destruction of the limbal stem cell niche, upon which the …

Extracellular matrix (ECM) proteins fill the space between cells in multicellular organisms,
contributing to the structure of organs and tissues. The mechanical properties of ECM are …

Angiogenesis plays a central role in human physiology from reproduction and fetal
development to wound healing and tissue repair/regeneration. Clinically relevant therapies …

Purpose: Corneal sensory nerves protect the cornea from injury. They are also thought to
stimulate limbal stem cells (LSCs) to produce transparent epithelial cells constantly …

Mesenchymal stem/stromal cells (MSCs) have broad application prospects for regenerative
medicine due to their self‐renewal, high plasticity, ability for differentiation, and immune …

Extracellular vesicles (EVs) are double membrane vesicles, abundant in all biological fluids.
However, the characterization of EVs in aqueous humor (AH) is still limited. The aim of the …

Dry eye disease (DED) is a growing public health concern affecting millions of people
worldwide and causing ocular discomfort and visual disturbance. Developing its therapeutic …

The corneal epithelium is composed of stratified squamous epithelial cells on the outer
surface of the eye, which acts as a protective barrier and is critical for clear and stable vision …

We aimed to investigate whether a novel technique of human amniotic membrane (HAM)
preparation that mimics the crypts in the limbus enhances the number of progenitor cells …