On the origin of degeneracy in the genetic code

DL Gonzalez, S Giannerini, R Rosa - Interface Focus, 2019 - royalsocietypublishing.org
The degeneracy of amino acid coding is one of the most crucial and enigmatic aspects of the
genetic code. Different theories about the origin of the genetic code have been developed …

Circular code motifs in transfer and 16S ribosomal RNAs: a possible translation code in genes

CJ Michel - Computational biology and chemistry, 2012 - Elsevier
In 1996, a common trinucleotide circular code, called X, is identified in genes of eukaryotes
and prokaryotes (Arquès and Michel, 1996). This circular code X is a set of 20 trinucleotides …

Circular codes, symmetries and transformations

E Fimmel, S Giannerini, DL Gonzalez… - Journal of Mathematical …, 2015 - Springer
Circular codes, putative remnants of primeval comma-free codes, have gained considerable
attention in the last years. In fact they represent a second kind of genetic code potentially …

Spontaneous evolution of circular codes in theoretical minimal RNA rings

J Demongeot, H Seligmann - Gene, 2019 - Elsevier
Small circular RNAs occur in many cells. Theoretical considerations designed to mimick
primordial RNAs designed 25 theoretical, minimal 22-nucleotide long circular RNAs (RNA …

The Maximal C3 Self-Complementary Trinucleotide Circular Code X in Genes of Bacteria, Archaea, Eukaryotes, Plasmids and Viruses

CJ Michel - Life, 2017 - mdpi.com
In 1996, a set X of 20 trinucleotides was identified in genes of both prokaryotes and
eukaryotes which has on average the highest occurrence in reading frame compared to its …

The maximal C3 self-complementary trinucleotide circular code X in genes of bacteria, eukaryotes, plasmids and viruses

CJ Michel - Journal of Theoretical Biology, 2015 - Elsevier
In 1996, a set X of 20 trinucleotides is identified in genes of both prokaryotes and eukaryotes
which has in average the highest occurrence in reading frame compared to the two shifted …

Circular code motifs in transfer RNAs

CJ Michel - Computational biology and chemistry, 2013 - Elsevier
In 1996, a trinucleotide circular code X is identified in genes of prokaryotes and eukaryotes
(Arquès and Michel, 1996). In 2012, X motifs are identified in the transfer RNA (tRNA) Phe …

Bijective transformation circular codes and nucleotide exchanging RNA transcription

CJ Michel, H Seligmann - Biosystems, 2014 - Elsevier
The C 3 self-complementary circular code X identified in genes of prokaryotes and
eukaryotes is a set of 20 trinucleotides enabling reading frame retrieval and maintenance, ie …

On the origin of the mitochondrial genetic code: towards a unified mathematical framework for the management of genetic information

DL Gonzalez, S Giannerini, R Rosa - 2012 - nature.com
The origin of the genetic code represents one of the most challenging problems in molecular
evolution. The genetic code is an important universal feature of extant organisms and …

Overlapping genetic codes for overlapping frameshifted genes in Testudines, and Lepidochelys olivacea as special case

H Seligmann - Computational Biology and Chemistry, 2012 - Elsevier
Mitochondrial genes code for additional proteins after+ 2 frameshifts by reassigning stops to
code for amino acids, which defines overlapping genetic codes for overlapping genes …