3 Role of natural products in treatment of diseases 4 Antiinfective agents (including
antimalarials) 4.1 Antibacterials: b-lactams 4.2 Antibacterials: aminoglycosides 4.3 …

Antibiotics—compounds that are literally 'against life'—are typically antibacterial drugs,
interfering with some structure or process that is essential to bacterial growth or survival …

Polyketide biosynthesis: a millennium review - Natural Product Reports (RSC Publishing)
DOI:10.1039/A909079G Royal Society of Chemistry View PDF VersionPrevious ArticleNext Article …

Many biologically active small‐molecule natural products produced by microorganisms
derive their activities from sugar substituents. Changing the structures of these sugars can …

Antibiotics are precious resources in the fight to combat bacterial infections caused by
pathogenic organisms. Vancomycin is one of the antibiotics of last resort in the treatment of …

A revolution in industrial microbiology was sparked by the discoveries of ther double-
sttranded structure of DNA and the development of trecombinant DNA technology …

Covering: 1985–2002. This review covers the highlights of combinatorial biosynthesis
applied on post-polyketide synthase modifying enzymes, such as oxygenases …

Although microorganisms are extremely good in presenting us with an amazing array of
valuable products, they usually produce them only in amounts that they need for their own …

Natural products with antibiotic activity have been central agents in human therapeutics over
the past fifty years. They are likely to remain crucial in the decades to come. These …

Many bioactive natural products are glycosylated compounds in which the sugars are
important or essential for biological activity. The isolation of several sugar biosynthesis gene …