Viral evasion of intracellular DNA and RNA sensing
The co-evolution of viruses with their hosts has led to the emergence of viral pathogens that
are adept at evading or actively suppressing host immunity. Pattern recognition receptors …
are adept at evading or actively suppressing host immunity. Pattern recognition receptors …
[HTML][HTML] Respiratory syncytial virus: from pathogenesis to potential therapeutic strategies
Z Shang, S Tan, D Ma - International Journal of Biological Sciences, 2021 - ncbi.nlm.nih.gov
Respiratory syncytial virus (RSV) is one of the most important viral pathogens causing
respiratory tract infection in infants, the elderly and people with poor immune function, which …
respiratory tract infection in infants, the elderly and people with poor immune function, which …
SARS-coronavirus open reading frame-9b suppresses innate immunity by targeting mitochondria and the MAVS/TRAF3/TRAF6 signalosome
CS Shi, HY Qi, C Boularan, NN Huang… - The Journal of …, 2014 - journals.aai.org
Coronaviruses (CoV) have recently emerged as potentially serious pathogens that can
cause significant human morbidity and death. The severe acute respiratory syndrome …
cause significant human morbidity and death. The severe acute respiratory syndrome …
Dissection of influenza infection in vivo by single-cell RNA sequencing
Y Steuerman, M Cohen, N Peshes-Yaloz, L Valadarsky… - Cell systems, 2018 - cell.com
The influenza virus is a major cause of morbidity and mortality worldwide. Yet, both the
impact of intracellular viral replication and the variation in host response across different cell …
impact of intracellular viral replication and the variation in host response across different cell …
Immunity to RSV in early-life
L Lambert, AM Sagfors, PJM Openshaw… - Frontiers in …, 2014 - frontiersin.org
Respiratory Syncytial Virus (RSV) is the commonest cause of severe respiratory infection in
infants, leading to over 3 million hospitalizations and around 66,000 deaths worldwide each …
infants, leading to over 3 million hospitalizations and around 66,000 deaths worldwide each …
An overview of anti-SARS-CoV-2 and anti-inflammatory potential of baicalein and its metabolite baicalin: insights into molecular mechanisms
Abstract The current Coronavirus Disease 2019 (COVID-19) pandemic, caused by the
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), is highly contagious …
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), is highly contagious …
Antiviral activity of human OASL protein is mediated by enhancing signaling of the RIG-I RNA sensor
Virus infection is sensed in the cytoplasm by retinoic acid-inducible gene I (RIG-I, also
known as DDX58), which requires RNA and polyubiquitin binding to induce type I interferon …
known as DDX58), which requires RNA and polyubiquitin binding to induce type I interferon …
RIG-I-like receptor regulation in virus infection and immunity
Highlights•A balance of phosphorylation and K63-linked ubiquitination regulates RIG-I.•RIG-
I and MAVS functions are modulated by alternative splicing and translation.•Subcellular …
I and MAVS functions are modulated by alternative splicing and translation.•Subcellular …
Host and viral modulation of RIG-I-mediated antiviral immunity
Y Liu, D Olagnier, R Lin - Frontiers in immunology, 2017 - frontiersin.org
Innate immunity is the first line of defense against invading pathogens. Rapid and efficient
detection of pathogen-associated molecular patterns via pattern-recognition receptors is …
detection of pathogen-associated molecular patterns via pattern-recognition receptors is …
Toward a new STATe: the role of STATs in mitochondrial function
JA Meier, AC Larner - Seminars in immunology, 2014 - Elsevier
Abstract Signal Transducers and Activators of Transcription (STATs) have been studied
extensively and have been associated with virtually every biochemical pathway. Until …
extensively and have been associated with virtually every biochemical pathway. Until …