cAMP-dependent pathway is one of the most significant signaling cascades in healthy and
neoplastic ovarian cells. Working through its major effector proteins—PKA and EPAC—it …

Cancer/testis antigens (CTAs) are a group of tumor antigens expressed in numerous cancer
tissues, as well as in the testis and placental tissues. There are over 200 CTAs supported by …

Tumor angiogenesis and inflammation, which play important roles in mediating tumor
proliferation and growth, should be inhibited to effectively regulate tumor progression …

Cancer development is a multifactorial process resulting from the aberrant activation of
multiple signaling pathways. It has become increasingly clear that the coordination of the …

Sperm develop from puberty in the seminiferous tubules, inside the blood‐testis barrier to
prevent their recognition as “non‐self” by the immune system, and it is widely assumed that …

Colorectal cancer is a very common cancer worldwide. Serum tumor-associated
autoantibodies (TAAbs), especially the anti-p53 autoantibody, may be promising biomarkers …

Background Colorectal cancer (CRC) ranks third among the estimated cancer cases and
cancer related mortalities in the Western world. Early detection and efficient therapy of CRC …

Patients with cancer tend to develop antibodies to autologous proteins. This phenomenon
has been observed across multiple cancer types, including bladder, lung, colon, prostate …

Asthenozoospermia is one of the leading causes of male infertility owing to a decline in
sperm motility. Herein, we determined if there is a correlation between RNASET2 content on …

Abstract Background Cancer-testis antigens (CTAs) are tumor antigens that are normally
expressed in the testes but are aberrantly expressed in several cancers. CTA …