M Adamaki, V Zoumpourlis - Pharmacology & therapeutics, 2021 - Elsevier
Prostate cancer (PCa) is one of the most commonly diagnosed malignancies and among the leading causes of cancer-related death worldwide. It is a highly heterogeneous disease …
RS Eapen, JP Buteau, P Jackson, C Mitchell, SF Oon… - European Urology, 2024 - Elsevier
Background High-risk localised prostate cancer (HRCaP) has high rates of biochemical recurrence;[177 Lu] Lu-PSMA-617 is effective in men with advanced prostate cancer …
G Tossetta, S Fantone, D Marzioni, R Mazzucchelli - Cancers, 2023 - mdpi.com
Simple Summary Several studies showed that oxidative stress is involved in cancer occurrence, development, progression chemoresistance and radio resistance. The nuclear …
M Sathekge, F Bruchertseifer, M Vorster… - Journal of Nuclear …, 2022 - Soc Nuclear Med
225Ac-PSMA-617, targeting the prostate-specific membrane antigen (PSMA), which is overexpressed on prostate cancer cells, has shown a remarkable therapeutic efficacy in …
Y Zhang, L He, A Sadagopan, T Ma, G Dotti… - Molecular cancer …, 2021 - AACR
Radiotherapy (RT) is a key treatment for prostate cancer. However, RT resistance can contribute to treatment failure. Prostate cancer stem cells (PCSCs) are radioresistant. We …
A Ali, B Mekhaeil, OD Biziotis, EE Tsakiridis… - Communications …, 2023 - nature.com
Radiotherapy is a non-invasive standard treatment for prostate cancer (PC). However, PC develops radio-resistance, highlighting a need for agents to improve radiotherapy response …
A Carlos-Reyes, MA Muñiz-Lino… - Frontiers in …, 2021 - frontiersin.org
Radiation therapy has been used worldwide for many decades as a therapeutic regimen for the treatment of different types of cancer. Just over 50% of cancer patients are treated with …
Aim To study the role of EGFR signaling in regulation of intrinsic resistance in prostate cancer. Materials and methods Radioresistant prostate carcinoma DU145 and PC-3 cells …
Y Li, MH Cho, SS Lee, DE Lee, H Cheong… - Journal of Controlled …, 2020 - Elsevier
Radiotherapy (RT) is a major modality for cancer treatment, along with surgery and chemotherapy. Despite its therapeutic effect, the recurrence and metastasis of tumors due to …