CA Dinarello - Nature Reviews Rheumatology, 2019 - nature.com
More than any other cytokine family, the 11 members of the IL-1 family are associated with innate immune responses, which occur in acute inflammation and chronic inflammatory …
DI Chen, J Shen, W Zhao, T Wang, L Han, JL Hamilton… - Bone research, 2017 - nature.com
Osteoarthritis (OA) is the most common degenerative joint disease and a major cause of pain and disability in adult individuals. The etiology of OA includes joint injury, obesity …
P Wojdasiewicz, ŁA Poniatowski… - Mediators of …, 2014 - Wiley Online Library
Osteoarthritis (OA) is the most common chronic disease of human joints. The basis of pathologic changes involves all the tissues forming the joint; already, at an early stage, it has …
NGM Thielen, PM van der Kraan, APM van Caam - Cells, 2019 - mdpi.com
Cartilage homeostasis is governed by articular chondrocytes via their ability to modulate extracellular matrix production and degradation. In turn, chondrocyte activity is regulated by …
A Mobasheri, M Batt - Annals of physical and rehabilitation medicine, 2016 - Elsevier
Introduction Osteoarthritis (OA) is one of the most common forms of arthritis. There is accumulating evidence to suggest that OA is an inflammatory disease of the entire synovial …
KC Navegantes, R de Souza Gomes… - Journal of translational …, 2017 - Springer
Macrophages and neutrophils are key components involved in the regulation of numerous chronic inflammatory diseases, infectious disorders, and especially certain autoimmune …
B Heidari - Caspian journal of internal medicine, 2011 - ncbi.nlm.nih.gov
Osteoarthritis (OA) a common disease of aged population and one of the leading causes of disability. Incidence of knee OA is rising by increasing average age of general population …
Purpose The aims of this article were to systematically review the literature about the mechanism of action of colchicine in the multimodal pathology of acute inflammation …
Synovial joints are complex structures that enable normal locomotion. Following injury, they undergo a series of changes, including a prevalent inflammatory response. This increases …