The 1996 originally established multiple sclerosis (MS) subtypes, based solely on clinical
impression and consensus, were revised in 2013 to review potential imaging and biological …

The 2010 McDonald criteria for the diagnosis of multiple sclerosis are widely used in
research and clinical practice. Scientific advances in the past 7 years suggest that they might …

The clinical use of MRI in patients with multiple sclerosis (MS) has advanced markedly over
the past few years. Technical improvements and continuously emerging data from clinical …

New evidence and consensus has led to further revision of the McDonald Criteria for
diagnosis of multiple sclerosis. The use of imaging for demonstration of dissemination of …

Clinically isolated syndrome (CIS) is a term that describes a first clinical episode with
features suggestive of multiple sclerosis (MS). It usually occurs in young adults and affects …

Background and objective: We explored which clinical and biochemical variables predict
conversion from clinically isolated syndrome (CIS) to clinically definite multiple sclerosis …

Multiple sclerosis (MS), is a chronic disease of the central nervous system (CNS)
characterized by loss of motor and sensory function, that results from immune-mediated …

Background Oligoclonal bands (OCBs) unique to the cerebrospinal fluid are used in the
diagnosis of multiple sclerosis (MS). The precise prevalence of OCBs in MS and clinically …

Multiple sclerosis (MS) is a common, complex neurological disease. The precise aetiology of
MS is not yet known, although epidemiological data indicate that both genetic and …

A prodrome is an early set of signs or symptoms that indicate the onset of a disease before
more typical symptoms develop. Prodromal stages are well recognized in some neurological …