Membrane-interacting antifungal peptides

C Struyfs, BPA Cammue, K Thevissen - Frontiers in cell and …, 2021 - frontiersin.org
The incidence of invasive fungal infections is increasing worldwide, resulting in more than
1.6 million deaths every year. Due to growing antifungal drug resistance and the limited …

Emerging and future strategies in the management of recalcitrant Candida auris

N Bandara, L Samaranayake - Medical Mycology, 2022 - academic.oup.com
Candida auris is an emerging, multi drug resistant fungal pathogen that has caused
infectious outbreaks in over 45 countries since its first isolation over a decade ago, leading …

The specification and function of enteroendocrine cells in Drosophila and mammals: a comparative review

X Guo, J Lv, R Xi - The FEBS Journal, 2022 - Wiley Online Library
Enteroendocrine cells (EECs) in both invertebrates and vertebrates derive from intestinal
stem cells (ISCs) and are scattered along the digestive tract, where they function in sensing …

Advancements in nanoparticle-based therapies for multidrug-resistant candidiasis infections: a comprehensive review

A Izadi, F Paknia, M Roostaee, SAA Mousavi… - …, 2024 - iopscience.iop.org
Candida auris, a rapidly emerging multidrug-resistant fungal pathogen, poses a global
health threat, with cases reported in over 47 countries. Conventional detection methods …

Mapping of the lipid-binding regions of the antifungal protein NFAP2 by exploiting model membranes

O Pavela, T Juhász, L Tóth, A Czajlik… - Journal of Chemical …, 2024 - ACS Publications
Fungal infections with high mortality rates represent an increasing health risk. The
Neosartorya (Aspergillus) fischeri antifungal protein 2 (NFAP2) is a small, cysteine-rich …

Candida auris, a singular emergent pathogenic yeast: its resistance and new therapeutic alternatives

L Fernandes, R Ribeiro, M Henriques… - European Journal of …, 2022 - Springer
Nowadays, fungal infections affect millions of people across the world. Candida auris, a new
emergent yeast, is a worrisome pathogen because it associates with a high rate of incidence …

Recent advances and future perspectives in the pharmacological treatment of Candida auris infections

DR Giacobbe, L Magnasco, C Sepulcri… - Expert Review of …, 2021 - Taylor & Francis
Introduction Candida auris is responsible for hospital outbreaks worldwide. Some C. auris
isolates may show concomitant resistance to azoles, echinocandins, and polyenes, thereby …

Fungal biofilms as a valuable target for the discovery of natural products that cope with the resistance of medically important fungi—Latest findings

E Butassi, L Svetaz, MC Carpinella, T Efferth… - Antibiotics, 2021 - mdpi.com
The development of new antifungal agents that target biofilms is an urgent need. Natural
products, mainly from the plant kingdom, represent an invaluable source of these entities …

Transcriptional profiling of the Candida auris response to exogenous farnesol exposure

Á Jakab, N Balla, Á Ragyák, F Nagy, F Kovács… - Msphere, 2021 - Am Soc Microbiol
The antifungal resistance threat posed by Candida auris necessitates bold and innovative
therapeutic options. Farnesol is a quorum-sensing molecule with a potential antifungal …

Navigating the fungal battlefield: cysteine-rich antifungal proteins and peptides from Eurotiales

J Holzknecht, F Marx - Frontiers in Fungal Biology, 2024 - frontiersin.org
Fungi are ubiquitous in the environment and play a key role in the decomposition and
recycling of nutrients. On the one hand, their special properties are a great asset for the …