Quantitative magnetic resonance imaging (qMRI) goes beyond conventional MRI, which
aims primarily at local image contrast. It provides specific physical parameters related to the …

Mapping tissue microstructure with MRI holds great promise as a noninvasive window into
tissue organization at the cellular level. Having originated within the realm of diffusion NMR …

Recent years have seen an increased understanding of the importance of myelination in
healthy brain function and neuropsychiatric diseases. Non-invasive microstructural magnetic …

Several MRI measures have been proposed as in vivo biomarkers of myelin, each with
applications ranging from plasticity to pathology. Despite the availability of these myelin …

Pathophysiological changes in the spinal cord white and grey matter resulting from injury
can be observed with MRI techniques. These techniques provide sensitive markers of …

Although iron is crucial for neuronal functioning, many aspects of cerebral iron biology await
clarification. The ability to quantify specific iron forms in the living brain would open new …

Conventional magnetic resonance images are usually evaluated using the image signal
contrast between tissues and not based on their absolute signal intensities. Quantification of …

Objectives Currently, multiple sclerosis is treated with anti-inflammatory therapies, but these
treatments lack efficacy in progressive disease. New treatment strategies aim to repair …

The dry mass and the orientation of biomolecules can be imaged without a label by
measuring their permittivity tensor (PT), which describes how biomolecules affect the phase …

The neocortex of the human brain is the seat of higher brain function. Modern imaging
techniques, chief among them magnetic resonance imaging (MRI), allow non-invasive …