Background Poly (lactic acid)(PLA) and poly (lactic-co-glycolic acid)(PLGA) are among the
well-documented FDA-approved polymers used for the preparation of safe and effective …

Research on the use of biodegradable polymers for drug delivery has been ongoing since
they were first used as bioresorbable surgical devices in the 1980s. For tissue engineering …

Chitosan (CS) is a natural polymer derived from chitin that has wide applications in drugs,
vaccines, and antigen delivery. The distinctive mucoadhesive, biocompatibility …

Mucosal surfaces are the first site of infection for most infectious diseases and oral
vaccination can provide protection as the first line of defense. Unlike systemic …

Tuberculosis (TB) has been and still is a global emergency for centuries. Prevention of
disease through vaccination would have a major impact on disease prevalence, but the only …

The absence of validated correlates of protection (CoPs) hampers the rational design and
clinical development of new tuberculosis vaccines. In this review, we provide an overview of …

Tuberculosis (TB) continues to pose a global threat for millennia, currently affecting over 2
billion people and causing 10.6 million new cases and 1.3 million deaths annually. The only …

Vaccination is the most cost-effective and sustainable way to prevent and eliminate
infectious diseases. Compared with traditional vaccines, novel vaccines have better stability …

The limitations of non-biodegradable polymers have paved the way for biodegradable
polymers in the pharmaceutical and biomedical sciences over the years. Poly (lactic-co …

The global incidence of tuberculosis remains unacceptably high, with new preventative
strategies needed to reduce the burden of disease. We describe here a method for the …