The first report demonstrating that prolonged endurance exercise promotes oxidative stress
in humans was published more than 4 decades ago. Since this discovery, many ensuing …

Oxidative stress is a critical factor in the pathogenesis and progression of diabetes and its
associated complications. The imbalance between reactive oxygen species (ROS) …

The body of evidence from the past three decades demonstrates that oxidative stress can be
involved in several diseases. This study aims to summarise the current state of knowledge …

Physical exercise represents a major challenge to whole-body homeostasis, provoking
acute and adaptative responses at the cellular and systemic levels. Different sources of …

The pivotal observation that muscular exercise is associated with oxidative stress in humans
was first reported over 45 years ago. Soon after this landmark finding, it was discovered that …

Ischemia reperfusion (IR), present in myocardial infarction or extremity injuries, is a major
clinical issue and leads to substantial tissue damage. Molecular mechanisms underlying IR …

Skeletal muscle fibers are malleable and undergo rapid remodeling in response to
increased contractile activity (ie, exercise) or prolonged periods of muscle inactivity (eg …

The global concept of oxidative stress is defined as “an imbalance between oxidants and
antioxidants in favor of the oxidants, leading to a disruption of redox signaling and control …

Background Exercise is widely recognised for its health enhancing benefits. Despite this, an
overproduction of reactive oxygen and nitrogen species (RONS), outstripping antioxidant …

Aim The aim of this study was to reveal the role of reactive oxygen and nitrogen species
(RONS) in exercise adaptations under physiological in vivo conditions and without the …