Acetylcholine (AC h) plays an important role in memory function and has been implicated in
aging‐related dementia, in which the impairment of hippocampus‐dependent learning …

Fear memory is the best-studied form of memory. It was thoroughly investigated in the past
60 years mostly using two classical conditioning procedures (contextual fear conditioning …

The Cre-loxP system is invaluable for spatial and temporal control of gene knockout,
knockin, and reporter expression in the mouse nervous system. However, we report varying …

Cognitive flexibility, the ability to adjust behavior in response to new and unexpected
conditions in the environment, is essential for adaptation to new challenges and survival …

In Alzheimer's disease, accumulation of soluble oligomers of β-amyloid peptide is known to
be highly toxic, causing disturbances in synaptic activity and neuronal death. Multiple …

Acetylcholine, the first chemical to be identified as a neurotransmitter, is packed in synaptic
vesicles by the activity of VAChT (vesicular acetylcholine transporter). A decrease in VAChT …

Acetylcholine (ACh) is an important neuromodulator in the nervous system implicated in
many forms of cognitive and motor processing. Recent studies have used bacterial artificial …

The Nucleus of the Solitary Tract (NTS) receives gustatory and visceral information from
afferent fibers in the vagus and projects to the Nucleus Paragigantocellularis (PGi), among …

Loss-of-function mutations of the gene Cul3 have been identified as a risk factor for autism-
spectrum disorder (ASD), but the pathogenic mechanisms are not well understood …

In Alzheimer's disease (AD), soluble amyloid-β oligomers (AβOs) trigger neurotoxic
signaling, at least partially, via the cellular prion protein (PrPC). However, it is unknown …