The trace element selenium (Se) is an essential part of the human diet; moreover, increased
health risks have been observed with Se deficiency. A sufficiently high Se status is a …

Iodothyronine deiodinases (DIO) are a family of selenoproteins controlling systemic and
local availability of the major thyroid hormone l-thyroxine (T4), a prohormone secreted by the …

This review traces the discoveries that led to the recognition of selenium (Se) as an essential
nutrient and discusses Se-responsive diseases in animals and humans in the context of …

Abstract Purpose of Review (Mal-) nutrition of micronutrients, like selenium, has great impact
on the human heart and improper micronutrient intake was observed in 30–50% of patients …

Human thioredoxin reductase (TrxR) is a selenoprotein with a central role in cellular redox
homeostasis, utilizing a highly reactive and solvent-exposed selenocysteine (Sec) residue in …

The brain has a very high oxygen consumption rate and is particularly sensitive to oxidative
stress. It is also the last organ to suffer from a loss of selenium (Se) in case of deficiency. Se …

Expression of selenoproteins is widespread in neurons of the central nervous system. There
is continuous evidence presented over decades that low levels of selenium or …

Selenium (Se) is an essential trace element that functions in the form of the 21st amino acid,
selenocysteine (Sec) in a defined set of proteins. Se deficiency is associated with …

Living systems are built from a small subset of the atomic elements, including the bulk
macronutrients (C, H, N, O, P, S) and ions (Mg, K, Na, Ca) together with a small but variable …

In this review, the relevance of selenium (Se) to viral disease will be discussed paying
particular attention to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and …