Avoiding pits on the energy landscape–alternative strategies for stabilizing nateglinide co-amorphous systems

JFC Silva, M Jasiurkowska-Delaporte, PSP Silva… - …, 2024 - pubs.rsc.org
Amorphous solid phases can be represented by shallow basins in the potential energy
hypersurface. Glasses formed by substances with prolific crystal polymorphism, such as …

Improved Pharmaceutical Properties of Honokiol via Salification with Meglumine: an Exception to Oft-quoted ∆pKa Rule

X He, Y Wei, S Wang, J Zhang, Y Gao, S Qian… - Pharmaceutical …, 2022 - Springer
Honokiol (HK), a BCS class II drug with a wide range of pharmacological activities, has poor
solubility and low oral bioavailability, severely limiting its clinical application. In the current …

Influence of alkalizers–capping agents on hydrothermal synthesis, phase content, magnetization and pseudocapacitive behavior of iron oxides

C Zhang, I Zhitomirsky - Journal of Materials Science, 2025 - Springer
A conceptually new approach is developed for hydrothermal synthesis of nanostructured
iron oxides for energy storage in anodes of supercapacitors. The use of biocompatible …

Development of rebamipide-loaded spray-dried microsphere using distilled water and meglumine: physicochemical characterization and pharmacokinetics in rats

DW Ko, JH Cho, HG Choi - Pharmaceutical Development and …, 2021 - Taylor & Francis
In this study, a novel rebamipide-loaded spray-dried microsphere (RSM) with enhanced
drug solubility and oral bioavailability has been developed utilizing meglumine, an …

Formulation, Optimization, In-Vitro and In-Vivo Evaluation of Nateglinide-Loaded Nanostructured Lipid Carriers for Enhanced Bioavailability

SS Tiwari, YD Dange, SM Honmane, MG Saralaya… - BioNanoScience, 2025 - Springer
Nateglinide (NTG) belongs to the meglitinide class, an oral hypoglycemic agent used in the
treatment of insulin-resistant (Type II) diabetes mellitus. Potential constraints associated with …

[引用][C] Influencia de la concentración del contraión meglumina en la velocidad de disolución de furosemida

KLV QUISPE - 2021 - Universidad Nacional Mayor de San …