Introduction Diabetes is a serious public health problem, with low-and middle-income countries (LMICs) bearing over 80% of the burden. Diabetic retinopathy (DR) is one of the …
B Bao, J Liu, T Li, Z Yang, G Wang, J Xin, H Bi… - Archives of Biochemistry …, 2023 - Elsevier
Objective This study aimed to investigate the regulatory role of the PI3K/AKT/ERK signaling pathway in retinal fibrosis in− 6.0 diopter (D) lens-induced myopic (LIM) guinea pigs …
E Pöstyéni, R Gábriel, A Kovács-Valasek - Pharmaceutics, 2024 - mdpi.com
Owing to its promiscuous roles, poly (ADP-ribose) polymerase-1 (PARP-1) is involved in various neurological disorders including several retinal pathologies. Diabetic retinopathy …
S Ben, Y Ma, Y Bai, Q Zhang, Y Zhao, J Xia, M Yao - Iscience, 2024 - cell.com
Inflammation-mediated crosstalk between neuroglial cells and endothelial cells (ECs) is a fundamental feature of many vascular diseases. Nevertheless, the landscape of …
N Kang, JS Jung, J Hwang, SE Park, M Kwon, H Yoon… - Biomedicines, 2024 - mdpi.com
Background: Diabetic retinopathy (DR) is a vision-threatening complication that affects virtually all diabetic patients. Various treatments have been attempted, but they have many …
Q Wang, C So, C Qiu, T Zhang, K Yang, F Pan - Experimental eye research, 2024 - Elsevier
This study aimed to investigate potential functional changes in retinal ganglion cells (RGCs) in a mouse model of hyperglycemia and explore possible therapeutic approaches …
B Flavin, A Schimel, Z Contreras, MH Shannon… - Journal of Managed …, 2024 - jmcp.org
Wet age-related macular degeneration (AMD) is an acquired degeneration of the retina that can lead to central vision impairment. It is primarily treated with intravitreal injections of …
Structura tezei: introducere, 3 capitole, concluzii generale și recomandări practice, 101 pagini de text de bază, bibliografie din 201 de titluri, 19 figuri și 7 tabele incluse în text, 5 …
JZ Heckman, A Tsin, S Villa - 2024 - scholarworks.utrgv.edu
Abstract Vascular Endothelial Growth Factor is a growth factor that plays a significant role in angiogenesis and vascular permeability. This paper dives into the development of diabetic …