[HTML][HTML] Bio-Metal Dyshomeostasis-Associated Acceleration of Aging and Cognitive Decline in Down Syndrome

K Ishihara, E Kawashita, S Akiba - Biological and Pharmaceutical …, 2023 - jstage.jst.go.jp
Down syndrome (DS), which is caused by triplication of human chromosome 21 (Hsa21),
exhibits some physical signs of accelerated aging, such as graying hair, wrinkles and …

Protective Effect of Quercetin against Paraquat-induced Brain Mitochondrial Disruption in Mice

P Saberi-Hasanabadi, R Sedaghatnejad… - Current Drug …, 2024 - ingentaconnect.com
Background: Paraquat is a highly toxic quaternary ammonium herbicide widely used in
agriculture. It is an agent that induces pulmonary toxicity via the redox cyclic reaction …

[HTML][HTML] 基于PI3K/AKT 通路探讨青光增视方对过氧化氢诱导的视网膜神经节细胞损伤的保护机制

姜艳华, 赵磊, 陈琳琳, 左韬 - 中国医科大学学报, 2023 - html.rhhz.net
目的探讨青光增视方对过氧化氢(H 2 O 2) 诱导的视网膜神经节细胞(RGC)-5
损伤的保护作用及其对磷脂酰肌醇3 激酶/蛋白激酶B (PI3K/AKT) 通路的调节作用. 方法通过H 2 …

miR-494-3p 靶向调控RCAN1 对高糖诱导的足细胞损伤的影响.

郭晓莉, 杜燕, 李莎莎, 袁二磊 - Journal of China Medical …, 2023 - search.ebscohost.com
摘要目的探讨miR-494-3p 对高糖(HG) 诱导的小鼠肾足细胞(MPC5) 损伤的影响及其对钙调
磷酸酶调节蛋白1 (RCAN1) 的调控作用. 方法HG 诱导MPC5 细胞建立细胞损伤模型 …