[HTML][HTML] KIF6 gene as a pharmacogenetic marker for lipid-lowering effect in statin treatment

C Ruiz-Iruela, A Padró-Miquel, X Pintó-Sala… - PLoS one, 2018 - journals.plos.org
Introduction The therapeutic response to statins has a high interindividual variability with
respect to reductions in plasma LDL-cholesterol (c-LDL) and increases in HDL cholesterol (c …

Post-transcriptional regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase: crucial role of microRNA-27a or Identification of microRNA-27a as a key regulator …

AA Khan, V Gupta, K Ananthamohan, V Arige… - bioRxiv, 2018 - biorxiv.org
Hydroxy-3-methylglutaryl-coenzyme A reductase gene (Hmgcr) that codes for the rate-
limiting enzyme in the cholesterol biosynthesis pathway is a key modulator of dyslipidemia …

MicroRNA-27a mitigates hyperlipidemia and atherosclerosis by modulating cholesterol homeostasis

AA Khan, H Agarwal, SS Reddy, V Arige, V Gupta… - bioRxiv, 2018 - biorxiv.org
Hypercholesterolemia is a strong predictor of cardiovascular diseases that result in the
largest number of mortality and morbidity worldwide. 3-Hydroxy-3-methylglutaryl-coenzyme …