Oleuropein: A natural antioxidant molecule in the treatment of metabolic syndrome

J Ahamad, I Toufeeq, MA Khan… - Phytotherapy …, 2019 - Wiley Online Library
Olive (Olea europaea Linn., Fam. Oleaceae) is commonly known as Zaytoon in
Mediterranean region. Its fruits and oil are essential components of Mediterranean diets …

Systemic health effects of oleuropein and hydroxytyrosol supplementation: A systematic review of randomized controlled trials

O Frumuzachi, LI Gavrilaș, DC Vodnar, S Rohn… - Antioxidants, 2024 - mdpi.com
Non-communicable diseases (NCDs) cause 41 million deaths annually, accounting for 74%
of global fatalities. The so-called Mediterranean diet, with its especially significant …

Oleuropein improves glucose tolerance and lipid profile in rats with simultaneous renovascular hypertension and type 2 diabetes

A Khalili, AA Nekooeian… - Journal of Asian natural …, 2017 - Taylor & Francis
Oleuropein mediates most of the beneficial effects of olive products. This study examined the
role of oxidative stress in the effects of oleuropein on lipid profile and blood glucose in rats …

The neuroprotection effect of pretreatment with olive leaf extract on brain lipidomics in rat stroke model

Z Rabiei, MR Bigdeli, B Rasoulian, A Ghassempour… - Phytomedicine, 2012 - Elsevier
BACKGROUND: Recent studies suggest that olive extracts suppress inflammation and
reduce stress oxidative injury. We have attempted to determine the effect of dietary olive leaf …

Pretreatment with oleuropein protects the neonatal brain from hypoxia-ischemia by inhibiting apoptosis and neuroinflammation

M Reyes-Corral, L Gil-González… - Journal of Cerebral …, 2024 - journals.sagepub.com
Hypoxic-ischemic (HI) encephalopathy is a cerebrovascular injury caused by oxygen
deprivation to the brain and remains a major cause of neonatal mortality and morbidity …

[HTML][HTML] Highly potent antioxidant Olea europaea L. leaf extract affects carotid and renal haemodynamics in experimental hypertension: The role of oleuropein

M Ivanov, UJ Vajic, N Mihailovic-Stanojevic… - EXCLI …, 2018 - ncbi.nlm.nih.gov
Haemodynamic alterations in carotid and renal arteries are associated with the severity of
target organ damage in patients with hypertension. Dietary habits, such as the …

[PDF][PDF] Olive leaf and its various health-benefitting effects: A review study

Z Kermanshah, H Samadanifard… - Pakistan Journal of …, 2020 - researchgate.net
Olive tree (Olea europaea L.) is an evergreen plant, cultivated ever since ancient times and
has widely been used in traditional medicine. Mediterranean diet, rich in olive and its …

[HTML][HTML] Oral administration of oleuropein and olive leaf extract has cardioprotective effects in rodents: A systematic review

RCR Menezes, KK Peres, MT Costa-Valle… - Revista Portuguesa de …, 2022 - Elsevier
Oleuropein is a polyphenol found in olive trees that has shown beneficial effects in animal
studies and potentially in human health, although few studies have been performed to …

Oleuropein prevents the development of experimental autoimmune myocarditis in rats

JY Zhang, Z Yang, K Fang, ZL Shi, DH Ren… - International …, 2017 - Elsevier
Oleuropein (OLE) is a natural secoiridoid that is derived from Olea europaea. OLE
possesses cardioprotective effects in experimental models of hypertension, myocardial …

Protective effect of oleuropein on ketamine-induced cardiotoxicity in rats

MS Çömez, M Cellat, H Özkan, Y Borazan… - Naunyn-Schmiedeberg's …, 2020 - Springer
The antioxidant and cardioprotective effects of oleuropein have been reported in several
studies; however, its effect on ketamine cardiotoxicity has not been known yet. The aim of …