Anaphylaxis is a severe, acute, life-threatening multisystem allergic reaction resulting from
the release of a plethora of mediators from mast cells culminating in serious respiratory …

Mast cells are distributed throughout the gastrointestinal tract and function as the main
effector cells of IgE-mediated allergic reactions to foods. Allergen-induced cross-linking of …

Anaphylaxis is a systemic hypersensitivity reaction that can be life threatening.
Mechanistically, it results from the immune activation and release of a variety of mediators …

B cells play a key role in our immune system through their ability to produce antibodies,
suppress a proinflammatory state, and contribute to central immune tolerance. We aim to …

Abstract Purpose of Review The purpose of this review is to provide a better understanding
of anaphylaxis pathophysiology and describe the underlying mechanisms, effector cells, and …

Background Rhinovirus (RV) infections are a major cause of asthma exacerbations. Unlike
other respiratory viruses, RV causes minimal cytotoxic effects on airway epithelial cells and …

Acute hypersensitivity reactions (AHRs) occurring in present-day anaesthesia can have
severe, sometimes fatal, consequences and their incidence is increasing. The most frequent …

Acute hypersensitivity reactions to drugs occur infrequently during anaesthesia and the peri-
operative period. When clinical presentation includes the classical triad, erythema …

This study aimed to analyze the role of the FcepsilonRI (FcεRI) signaling pathway in the
pathogenesis of benign lymphoepithelial lesion of lacrimal gland (LGBLEL). Transcriptomic …

Autoantigen-specific immunotherapy using peptides offers a more targeted approach to treat
autoimmune diseases, but clinical implementation has been challenging. We previously …