Single-cell sequencing technologies have revolutionized biomedical research by enabling deconvolution of cell type-specific properties in highly heterogeneous tissue. While robust …
Schizophrenia is a debilitating neuropsychiatric disorder with heterogenous symptoms across three key domains: positive, negative and cognitive symptoms. Current therapeutic …
The epigenome underlies cell type and state and in post-mitotic neurons, and it regulates the ability for rapid response to activity. Since neurons exit the cell cycle early in …