[HTML][HTML] Rapid multiplex PCR for respiratory viruses reduces time to result and improves clinical care: Results of a systematic review and meta-analysis

TW Clark, K Lindsley, TB Wigmosta, A Bhagat… - Journal of Infection, 2023 - Elsevier
Objectives The clinical impact of rapid sample-to-answer “syndromic” multiplex polymerase
chain reaction (PCR) testing for respiratory viruses is not clearly established. We performed …

[HTML][HTML] Leveraging diagnostic stewardship within antimicrobial stewardship programmes

KC Claeys, MD Johnson - Drugs in Context, 2023 - ncbi.nlm.nih.gov
Novel diagnostic stewardship in infectious disease consists of interventions that modify
ordering, processing, and reporting of diagnostic tests to provide the right test for the right …

Multicenter evaluation of the QIAstat-Dx respiratory panel for detection of viruses and bacteria in nasopharyngeal swab specimens

AL Leber, JG Lisby, G Hansen, RF Relich… - Journal of clinical …, 2020 - Am Soc Microbiol
ABSTRACT The QIAstat-Dx Respiratory Panel (QIAstat-Dx RP) is a multiplex in vitro
diagnostic test for the qualitative detection of 20 pathogens directly from nasopharyngeal …

Appropriate use and future directions of molecular diagnostic testing

EH Graf, P Pancholi - Current Infectious Disease Reports, 2020 - Springer
Abstract Purpose of Review Major technologic advances in two main areas of molecular
infectious disease diagnostics have resulted in accelerated adoption or ordering, outpacing …

Impact of multiplexed respiratory viral panels on infection control measures and antimicrobial stewardship: a review of the literature

J Wils, V Saegeman, A Schuermans - European Journal of Clinical …, 2022 - Springer
Multiplexed respiratory viral panels (MRVP) have recently been added to the diagnostic
work-up of respiratory infections. This review provides a summary of the main literature of …

Targeted rapid testing for SARS-CoV-2 in the emergency department is associated with large reductions in uninfected patient exposure time

JS Hinson, RE Rothman, K Carroll, HH Mostafa… - Journal of Hospital …, 2021 - Elsevier
Opportunity exists to decrease healthcare-related exposure to severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2), preserve infection control resources, and increase …

Epidemiology and clinical manifestations of different enterovirus and rhinovirus types show that EV‐D68 may still have an impact on severity of respiratory infections

SB Larsson, D Vracar, M Karlsson… - Journal of Medical …, 2022 - Wiley Online Library
Respiratory infections are often caused by enteroviruses (EVs). The aim of this study was to
identify whether certain types of EV were more likely to cause severe illness in 2016, when …

Utility of the respiratory viral panel as an antimicrobial stewardship tool

K Covert, E Bashore, MK Edds… - Journal of Clinical …, 2021 - Wiley Online Library
Abstract What is Known and Objective The development of rapid diagnostics has
revolutionized antimicrobial stewardship with efforts targeting earlier de‐escalation or …

Diagnosis, Treatment, and Prevention Resources for Infectious Diseases in Sub-Saharan African Hospitals Caring for Children

S Tarun, W Abebe, M Mahida, L Saiman… - Global Pediatric …, 2023 - journals.sagepub.com
Objective. The Children's Hospitals in Africa Mapping Project survey was developed and
implemented to assess the readiness of hospitals in sub-Saharan African to respond to …

Outpatient antibiotic and antiviral utilization patterns in patients tested for respiratory pathogens in the United States: A real-world database study

J Tse, AM Near, M Cheng, J Karichu, B Lee, SN Chang - Antibiotics, 2022 - mdpi.com
This retrospective observational study evaluated outpatient treatment patterns among
patients with molecular-based viral diagnostic testing for suspected upper respiratory tract …