The gut microbiota in thrombosis

MP Khuu, N Paeslack, O Dremova, C Benakis… - Nature Reviews …, 2024 - nature.com
The gut microbiota has emerged as an environmental risk factor that affects thrombotic
phenotypes in several cardiovascular diseases. Evidence includes the identification of …

Effect of TMAO on the incidence and prognosis of cerebral infarction: a systematic review and meta-analysis

L Wang, Y Nan, W Zhu, S Wang - Frontiers in Neurology, 2024 - frontiersin.org
Objective This study aimed to evaluate the effect of trimethylamine oxide (TMAO) on the
incidence and prognosis of cerebral infarction. Methods We searched PubMed, Embase …

Berberine promotes the degradation of phenylacetic acid to prevent thrombosis by modulating gut microbiota

HJ Zhang, J Fu, H Yu, H Xu, JC Hu, JY Lu, MM Bu… - Phytomedicine, 2024 - Elsevier
Background Berberine is the main bioactive constituent of Coptis chinensis, a quaternary
ammonium alkaloid. While berberine's cardiovascular benefits are well-documented, its …

Association between plasma trimethylamine N-oxide and cerebral white matter hyperintensity: a cross-sectional study

X Ji, X Zhang, J Zhang, S Niu, HC Xiao… - Frontiers in Aging …, 2024 - frontiersin.org
Background Cerebral white matter hyperintensity (WMH) is a pivotal imaging feature of
cerebral small vessel disease (CSVD), closely correlated with an elevated risk of ischemic …

[HTML][HTML] Gut Microbe-Generated Metabolite Trimethylamine-N-Oxide and Ischemic Stroke

Z Li, X He, Q Fang, X Yin - Biomolecules, 2024 - mdpi.com
Trimethylamine-N-oxide (TMAO) is a gut microbiota-derived metabolite, the production of
which in vivo is mainly regulated by dietary choices, gut microbiota, and the hepatic enzyme …

Causal relationship of inflammatory cytokines and serum metabolites in cerebral small vessel disease: a two‐step Mendelian randomization study

Z Li, L Miao, T Zhang, AM Thomas… - European Journal of …, 2024 - Wiley Online Library
Background and purpose The aim was to investigate the causal relationships of
inflammatory cytokines and serum metabolites in cerebral small vessel disease (CSVD) …

基于网络药理学, 分子对接及实验验证探讨益气通脉散抗脑缺血再灌注损伤的作用机制.

宋鹏鹏, 郭燕可, 关东升, 马鸣… - … Chinese Drug Research …, 2024 - search.ebscohost.com
目的基于网络药理学, 分子对接及实验验证探讨益气通脉散(人参, 丹参, 三七, 水蛭, 土鳖虫, 大黄)
抗脑缺血再灌注损伤(CIRI) 的作用机制. 方法(1) 通过TCMSP, TCMID, ETCM …