The high incidence of cardiomyopathy in patients with hemosiderosis, particularly in
transfusional iron overload, strongly indicates that iron accumulation in the heart plays a …

Objectives: Recent advancements have promoted the use of T2* magnetic resonance
imaging (MRI) in the non-invasive detection of iron overload in various organs for …

Introduction: In this study, we aimed to assess the relationship of cardiac and hepatic T2*
magnetic resonance imaging (MRI) values as a gold standard for detecting iron overload …

Background To assess the prevalence trend and contributing factors of heart failure (HF)
impairment with thalassemias at global, regional and national levels. Methods Data on HF …

We aimed to evaluate the role of two-dimensional speckle tracking imaging (2DSTI) in
detecting early changes of myocardial deformation in patients affected by thalassemia major …

Beta-thalassaemia is a genetic disease with different clinical aspects, which can lead to
heart failure with a multifactorial mechanism. Over the last years, growing interest has been …

Background The purpose of this study is to determine early myocardial dysfunction in β‐
thalassemia major (BTM) patients. Where the myocardial dysfunction cannot be detected by …

Background: Cardiac iron overload is the most serious complication in thalassemia; even
patients treated with intensive chelation suffer at a certain point from cardiomyopathy and …

Heart failure caused by iron deposits in the myocardium is the primary cause of mortality in
beta-thalassemia major patients. Cardiac magnetic resonance imaging (CMRI) T2* is the …

Background: Cardiac iron toxicity is a major cause of mortality in transfusion-dependent beta-
thalassemia major patients. The main modality for detecting cardiac iron toxicity is MRI T2 …